Nausch H, Knödler M, Buyel JF (2024) Production of complex proteins – from plant molecular farming to manufacturing. In Pörtner R (ed) Biopharmaceutical Manufacturing - Progress, Trends and Challenges. Cell Engineering 11. Springer, Cham, pp 241–278.  DOI

Buntru M, Vogel S, Finnern R, Schillberg S (2022) Plant-based cell-free transcription and translation of recombinant proteins. In: Schillberg S, Spiegel H (eds) Recombinant Proteins in Plants. Methods in Molecular Biology 2480. Humana, New York, NY, pp 113–124.  DOI

Buyel JF (2022) Statistical designs to improve downstream processing. In: Schillberg S, Spiegel H (eds) Recombinant Proteins in Plants. Methods in Molecular Biology 2480. Humana Press, New York, NY, pp 295–310.  DOI

Buyel JF (2022) Strategies for efficient and sustainable protein extraction and purification from plant tissues. In: Schillberg S, Spiegel H (eds) Recombinant Proteins in Plants. Methods in Molecular Biology 2480. Humana Press, New York, NY, pp 127–145.  DOI

Dickmeis C, Commandeur U (2022) Advanced fusion strategies for the production of functionalized potato virus X virions. In: Schillberg S, Spiegel H (eds) Recombinant Proteins in Plants. Methods in Molecular Biology 2480. Humana Press, New York, NY, pp 215–239.  DOI

Hundleby PAC, D’Aoust MA, Finkle C, Atkins J, Twyman RM (2022) Regulation of molecular farming products. In: Schillberg S, Spiegel H (eds) Recombinant Proteins in Plants. Methods in Molecular Biology 2480. Humana Press, New York, NY, pp 313–333.  DOI

Masani MYA, Parveez GKA, Noll G, Fizree MDPMAA, Sambanthamurthi R, Prüfer D (2022) Protoplast isolation and transformation in oil palm. In: Wang K, Zhang F (eds) Protoplast Technology. Methods in Molecular Biology 2464, Humana, New York, NY, pp 187–202.  DOI

Schillberg S, Spiegel H (2022) Recombinant protein production in plants: a brief overview of strengths and challenges. In: Schillberg S, Spiegel H (eds) Recombinant Proteins in Plants. Methods in Molecular Biology 2480. Humana Press, New York, NY, pp 1–13.  DOI

Spiegel H (2022) Improving recombinant protein recovery from plant tissue using heat precipitation. In: Schillberg S, Spiegel H (eds) Recombinant Proteins in Plants. Methods in Molecular Biology 2480. Humana Press, New York, NY, pp 147–157.  DOI

Spiegel H, Schillberg S, Nölke G (2022) Production of recombinant proteins by agrobacterium-mediated transient expression. In: Schillberg S, Spiegel H (eds) Recombinant Proteins in Plants. Methods in Molecular Biology 2480. Humana Press, New York, NY, pp 89–102.  DOI

Lampis S, Vallini G (2021) Microbial reduction of selenium oxyanions: energy-yielding and detoxification reactions. In Lens PNL, Pakshirajan K (eds) Environmental Technologies to Treat Selenium Pollution: Principles and Engineering. IWA Publishing, London, pp 101–143.  DOI

Hirsch R, Wiesner J, Marker A, Bauer A, Hammann PE, Vilcinskas A (2020) Biological profiling of coleoptericins and coleoptericin-like antimicrobial peptides from the invasive harlequin ladybird Harmonia axyridis. In: Donelli G (ed) Advances in Microbiology, Infectious Diseases and Public Health. Advances in Experimental Medicine and Biology 1214. Springer International, Cham, Switzerland, pp 43–59.  DOI

Käßer L, Zitzmann J, Grein T, Weidner T, Salzig D, Czermak P (2020) Turbidimetry and dielectric spectroscopy as process analytical technologies for mammalian and insect cell cultures. In: Pörtner R (ed) Animal Cell Biotechnology. Methods in Molecular Biology 2095. Humana Press, New York, NY, pp 335–364.  DOI

Nölke G, Schillberg S (2020) Strategies to enhance photosynthesis for the improvement of crop yields. In: Kumar A, Yau YY, Ogita S, Scheibe R (eds) Climate Change, Photosynthesis and Advanced Biofuels. Springer, Singapore, pp 143–157.  DOI

Vilcinskas A (2020) Insect biotechnology. In: Neugebauer R (ed) Biological Transformation. Springer Vieweg, Berlin, Heidelberg, Germany, pp 247–260.  DOI

Wen AM, Lee KL, Steinmetz NF (2020) Plant virus-based nanotechnologies. In: Norris P, Friedersdorf L (eds) Women in Nanotechnology. Women in Engineering and Science. Springer International, Cham, Switzerland, pp 57–69.  DOI

Barekzai J, Petry F, Zitzmann J, Czermak P, Salzig D (2019) Bioprocess development for human mesenchymal stem cell therapy products. In: Martínez-Espinosa RM (ed) New Advances on Fermentation Processes. Intech Open, London, UK.  DOI

Hoffmann D, Leber J, Loewe D, Lothert K. Oppermann T, Zitzmann J, Weidner T, Salzig D, Wolff M, Czermak P (2019) Purification of new biologicals using membrane-based processes. In: Basile A, Charcosset C (eds) Current Trends and Future Developments on (Bio-) Membranes. Membrane Processes in the Pharmaceutical and Biotechnological Field. Elsevier, Amsterdam, Netherlands, pp 123–150.  DOI

Mukherjee K, Vilcinskas A (2019) Transgenerational epigenetic inheritance in insects. In: Tollefsbol TO (ed) Transgenerational Epigenetics (Second Edition). Academic Press/Elsevier, London, UK, pp 315–329.  DOI

Fischer R, Holland T, Sack M, Schillberg S, Stoger E, Twyman RM, Buyel JF (2018) Glyco-engineering of plant-based expression systems. In: Rapp E, Reichl U (eds) Advances in Glycobiotechnology. Advances in Biochemical Engineering/Biotechnology 175. Springer International, Cham, Switzerland, pp 137–166.  DOI

Holland T, Buyel JF (2018) Bioreactor-based production of glycoproteins in plant cell suspension cultures. In: Picanço-Castro V, Swiech K (eds) Recombinant Glycoprotein Production. Methods in Molecular Biology 1674. Humana Press, New York, NY, pp 129–146.  DOI

Hundleby PAC, Sack M, Twyman RM (2018) Biosafety, risk assessment and regulation of molecular farming. In: Kermode A, Jiang L (eds) Molecular Pharming: Applications, Challenges and Emerging Areas. John Wiley & Sons, Inc., Hoboken, NJ, pp 329–351.  DOI

Kallepalli A, Soori U, James DB, Richardson MA (2019) Progress towards recalibration of spectrographs. 2018 IEEE British and Irish Conference on Optics and Photonics (BICOP), Royal Society, London, 12-14 December 2018.  DOI

McElroy C, Jennewein S (2018) Taxol® biosynthesis and production: from forests to fermenters. In: Schwab W, Lange B, Wüst M (eds) Biotechnology of Natural Products. Springer International, Cham, Switzerland, pp 145–185.  DOI

Pohlscheidt M, Kiss R, Gottschalk U (2018) An introduction to recent trends in the biotechnology industry: development and manufacturing of recombinant antibodies and proteins. In: Kiss B, Gottschalk U, Pohlscheidt M (eds) New Bioprocessing Strategies: Development and Manufacturing of Recombinant Antibodies and Proteins. Advances in Biochemical Engineering/Biotechnology 165. Springer International, Cham, Switzerland, pp 1–8.  DOI

Schoenherr S, Ebrahimi M, Czermak P (2018) Lignin degradation processes and the purification of valuable products. In: Poletto M (ed) Lignin: Trends and Applications. IntechOpen, London, UK, pp 29–63.  DOI

Spiegel H, Stöger E, Twyman RM, Buyel JF (2018) Current status and perspectives of the molecular farming landscape. In: Kermode A, Jiang L (eds) Molecular Pharming: Applications, Challenges and Emerging Areas. John Wiley & Sons, Inc., Hoboken, NJ, pp 3–23.  DOI

Allen L (2017) The evolution of platform technologies for the downstream processing of antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 365–390.  DOI

Andreolli M, Lampis S, Vallini G (2017) Diversity, distribution and functional role of bacterial endophytes in Vitis vinifera. In: Maheshwari DM (ed) Endophytes: Biology and Biotechnology, Volume 1. Sustainable Development and Biodiversity 15. Springer International, Cham, Switzerland, pp 233–266.  DOI

Arunakumari A, Wang J (2017) Purification of human monoclonal antibodies: non-protein A strategies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 135–154.  DOI

Buyel JF (2017) How plants can contribute to the supply of anti-cancer compounds. In: Malik S (ed) Biotechnology and Production of Anti-Cancer Compounds. Springer International, Cham, Switzerland, pp 39–72.  DOI

Buyel JF, Twyman RM, Fischer R (2017) Very-large-scale production of monoclonal antibodies in plants. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 655–672.  DOI

Chabanne C, Santarelli X (2017) Purification of IgM and IgA. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 615–630.  DOI

Curling J (2017) The development of antibody purification technologies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 23–54.  DOI

Elseberg C, Leber J, Weidner T, Czermak P (2017) The challenge of human mesenchymal stromal cell expansion: current and prospective answers. In: Gowder SJT (ed) New Insights into Cell Culture Technology. IntechOpen, London, UK, pp 99–134.  DOI

Etzel MR, Arunkumar A (2017) Charged ultrafiltration and microfiltration membranes for antibody purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 247–268.  DOI

Farid SS (2017) Process economic drivers in industrial monoclonal antibody manufacture. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 445–466.  DOI

Fontes N, Van Reis R (2017) Advances in technology and process development for industrial scale monoclonal antibody purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 199–214.  DOI

Gagnon P (2017) Purification of monoclonal antibodies by mixed mode chromatography. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 181–198.  DOI

Garonzi M, Centomo C, Delledonne M (2017) Next generation sequencing for next generation diagnostics and therapies. In: Nadin M (ed) Anticipation and Medicine. Springer International, Cham, Switzerland, pp 87–102.  DOI

Ghose S, Jin M, Liu J, Hickey J, Lee S (2017) Integrated polishing steps for monoclonal antibody purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 303–324.  DOI

Glynn J (2017) Process-scale precipitation of impurities in mammalian cell culture broth. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 233–246.  DOI

Grein TA, Weidner T, Czermak P (2017) Concepts for the production of viruses and viral vectors in cell cultures. In: Gowder SJT (ed) New Insights into Cell Culture Technology. IntechOpen, London, UK, pp 173–192.  DOI

Hahn T, Huuk T, Hubbuch J (2017) High-throughput screening and modeling technologies for process development in antibody purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 515–536.  DOI

Kelley B (2017) Downstream processing of monoclonal antibodies: current practices and future opportunities. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 1–22.  DOI

Li Y, Zhu M, Luo H, Weaver JR (2017) Development of a platform process for the purification of therapeutic monoclonal antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 343–364.  DOI

Mahler H-C, Mathäs R (2017) Trends in formulation and drug delivery for antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 673–698.  DOI

Mothes B (2017) Accelerated seamless antibody purification: simplicity is key. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 431–444.  DOI

Müller-Späth T, Morbidelli M (2017) Continuous chromatography for the purification of monoclonal antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 391–408.  DOI

Nikolov ZL, Regan JT, Dickey LF, Woodard SL (2017) Purification of antibodies from plants. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 631–654.  DOI

Pujar N, Low D, O’Leary R (2017) Antibody purification: drivers of change. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 699–716.  DOI

Rohrer T (2017) Manufacturing concepts for antibody–drug conjugates. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 595–614.  DOI

Schillberg S, Raven N, Fischer R, Twyman RM, Schiermeyer A (2017) Contained molecular farming using plant cell and tissue cultures. In: Yoshida T (ed) Applied Bioengineering. Innovations and Future Directions. Wiley-VCH Verlag GmbH, Weinheim, Germany, pp 261–281.  DOI 

Shukla AA, Norman CL (2017) Downstream processing of Fc fusion proteins, bispecific antibodies and antibody–drug conjugates. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 559–594.  DOI

Shukla AA, Suda E (2017) Harvest and recovery of monoclonal antibodies: cell removal and clarification. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 55–80.  DOI

Sinclair A (2017) Design and optimization of manufacturing. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 467–494.  DOI

Singh N, Chollangi S (2017) Next-generation clarification technologies for the downstream processing of antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 81–112.  DOI

Spitali M (2017) Downstream processing of monoclonal antibody fragments. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 537–558.  DOI

Thömmes J, Twyman RM, Gottschalk U (2017) Alternatives to packed-bed chromatography for antibody extraction and purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 215–232.  DOI

Tingley SK (2017) Disposable prepacked bed chromatography for downstream purification: form, fit, function and industry adoption. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 269–302.  DOI

Vajda J, Müller E (2017) Hydrophobic interaction chromatography for the purification of antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 155–180.  DOI

Vilcinskas A (2017) The impact of parasites on host insect epigenetics. In: Verlinden H (ed) Insect Epigenetics. Advances in Insect Physiology 53. Academic Press, London, UK, pp 145–165.  DOI

Vunnum S, Vedantham G, Hubbard B (2017) Protein A-based affinity chromatography. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 113–134.  DOI

Zhou JX (2017) Orthogonal virus clearance applications in monoclonal antibody production. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 325–342.  DOI

Zhou JX, Li J, Cui M, Chen H (2017) Smart design for an efficient facility with a validated disposable system. In: Gottschalk U (ed) Process Scale Purification of Antibodies (Second Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 495–514.  DOI

Zitzmann J, Sprick G, Weidner T, Schreiber C, Czermak P (2017) Process optimization for recombinant protein expression in insect cells. In: Gowder SJT (ed) New Insights into Cell Culture Technology. IntechOpen, London, UK, pp 43–97.  DOI

Baudach AF, Mukherjee K (2016) Epigenetic control of polyphenism in aphids. In: Vilcinskas A (ed) Biology and Ecology of Aphids. CRC Press, Boca Raton, FL, pp 89–99.  DOI

Bellin D, Delledonne M, Vandelle E (2016) Detection of peroxynitrite in plants exposed to bacterial infection. In: Gupta KJ (ed) Plant Nitric Oxide Methods and Protocols. Methods in Molecular Biology 1424. Humana Press, New York, NY, pp 191–200.  DOI

Boes A, Reimann A, Twyman RM, Fischer R, Schillberg S, Spiegel H (2016) A plant-based transient expression system for the rapid production of malaria vaccine candidates. In: Thomas S (ed) Vaccine Design Methods and Protocols, Volume 2 Vaccines for Veterinary Diseases. Methods in Molecular Biology 1404. Humana Press, New York, NY, pp 597–619.  DOI

Peschen D, Schillberg S, Fischer R (2016) Antibody-mediated pathogen resistance in plants. In: MacDonald J, Kolotilin I, Menassa R (eds) Recombinant Proteins from Plants. Methods in Molecular Biology 1385. Humana Press, New York, NY, pp 273–291.  DOI

Skaljac M (2016) Bacterial symbionts of aphids (Hemiptera: Aphididae). In: Vilcinskas A (ed) Biology and Ecology of Aphids. CRC Press, Boca Raton, FL, pp 100–125.  DOI

Vilcinskas A (2016) Aphid immunity. In: Vilcinskas A (ed) Biology and Ecology of Aphids. CRC Press, Boca Raton, FL, pp 126–134.  DOI

Vilcinskas A, Schmidtberg H (2016) The ontogenesis of the pea aphid Acyrthosiphon pisum. In: Vilcinskas A (ed) Biology and Ecology of Aphids. CRC Press, Boca Raton, FL, pp 14–51.  DOI

Will T (2016) Aphid techniques. In: Vilcinskas A (ed) Biology and Ecology of Aphids. CRC Press, Boca Raton, FL, pp 255–270.  DOI

Cremer C, Hehmann-Titt G, Schiffer S, Melmer G, Carloni P, Barth S, Nachreiner T (2015) Engineered versions of granzyme B and angiogenin overcome intrinsic resistance to apoptosis mediated by human cytolytic fusion proteins. In: Verma RS, Bonavida B (eds) Resistance to Immunotoxins in Cancer Therapy. Resistance to Targeted Anti-Cancer Therapeutics Volume 6. Springer International, Cham, Switzerland, pp 185–219.  DOI

Fischer R, Buyel JF, Schillberg S, Twyman RM (2014) Molecular farming in plants: the long road to the market. In: Howard JA, Hood EE (eds) Commercial Plant-Produced Recombinant Protein Products. Biotechnology in Agriculture and Forestry 68. Springer, Berlin, Heidelberg, Germany, pp 27–41.

Joop G, Vilcinskas A (2014) Evolutionary ecology of insect immunity. In: Hoffmann KH (ed) Insect Molecular Biology and Ecology. CRC Press, Boca Raton, FL, pp 271–290.

Shukla AA, Gottschalk U (2014) Downstream processing of Fc-fusion proteins. In: Chamow SM, Ryll T, Lowman HB, Farson D (eds) Therapeutic Fc-Fusion Proteins. Wiley-VCH Verlag GmbH, Weinheim, Germany, pp 97–114.

Worden N, Girke T, Drakakaki G (2014) Endomembrane dissection using chemically induced bioactive clusters. In: Hicks GR, Robert S (eds) Plant Chemical Genomics. Methods in Molecular Biology 1056. Humana Press, New York, NY, pp 159–168.

Barth S, Gattenlöhner S, Tur MK (2013) Immunokinases. In: Schmidt SR (ed) Fusion Protein Technologies for Biopharmaceuticals: Applications and Challenges. John Wiley & Sons, Inc., Hoboken, NJ, pp 329–336.

Brandt A, Vilcinskas A (2013) The fruit fly Drosophila melanogaster as a model for aging research. In: Vilcinskas A (ed) Yellow Biotechnology I: Insect Biotechnology in Drug Discovery and Preclinical Research. Advances in Biochemical Engineering/Biotechnology 135. Springer, New York, NY, pp 63–77.

Farré G, Naqvi S, Sanahuja G, Zorrilla-López U, Sanahuja G, Berman J, Sandman G, Ros G, Lopez-Nicolas R, Twyman RM, Christou P, Capell T, Zhu C (2013) Transgenic multivitamin biofortified corn: science, regulation, and politics. In: Preedy VR, Srirajaskanthan R, Patel VB (eds) Handbook of Food Fortification and Health: From Concepts to Public Health Applications Volume 1. Nutrition and Health. Springer, New York, NY, pp 335–347.

Fischer R, Ostafe R, Twyman RM (2013) Cellulases from insects. In: Vilcinskas A (ed) Yellow Biotechnology II: Insect Biotechnology in Plant Protection and Industry. Advances in Biochemical Engineering/Biotechnology 136. Springer, New York, NY, pp 51–64.

Knorr E, Bingsohn L, Kanost MR, Vilcinskas A (2013) Tribolium castaneum as a model for high-throughput RNAi screening. In: Vilcinskas A (ed) Yellow Biotechnology II: Insect Biotechnology in Plant Protection and Industry. Advances in Biochemical Engineering/Biotechnology 136. Springer, New York, NY, pp 163–178.

Mukherjee K, Raju R, Fischer R (2013) Galleria mellonella as a model host to study gut microbe homeostasis and brain infection by the human pathogen Listeria monocytogenes. In: Vilcinskas A (ed) Yellow Biotechnology I: Insect Biotechnology in Drug Discovery and Preclinical Research. Advances in Biochemical Engineering/Biotechnology 135. Springer, New York, NY, pp 27–39.

Schott M, Wehrenfennig C, Gasch T (2013) Insect antenna-based biosensors for in situ detection of volatiles. In: Vilcinskas A (ed) Yellow Biotechnology II: Insect Biotechnology in Plant Protection and Industry. Advances in Biochemical Engineering/Biotechnology 136. Springer, New York, NY, pp 101–122.

Will T, Vilcinskas A (2013) Aphid-proof plants: biotechnology-based approaches for aphid control. In: Vilcinskas A (ed) Yellow Biotechnology II: Insect Biotechnology in Plant Protection and Industry. Advances in Biochemical Engineering/Biotechnology 136. Springer, New York, NY, pp 179–203.

DalCorso G (2012) Heavy metal toxicity in plants. In: Furini A (ed) Plants and Heavy Metals: Springer Briefs in Molecular Science. Springer, New York, NY, pp 1–25.

Fasani E (2012) Plants that hyperaccumulate heavy metals. In: Furini A (ed) Plants and Heavy Metals: Springer Briefs in Molecular Science. Springer, New York, NY, pp 55–74.

Gottschalk U (2012) Downstream processing. In: Kayser O, Warzecha H (eds) Pharmaceutical Biotechnology: Drug Discovery and Clinical Applications (Second Edition). Wiley-VCH Verlag GmbH, Weinheim, Germany, pp 179–200.

Janzen C, Hoffmann K (2012) Optical measurements for the rational screening of protein crystallization conditions. In: Popp J, Tuchin VV, Chiou A, Heinemann SH (eds) Handbook of Biophotonics, Volume 3. John Wiley & Sons, Inc., Hoboken, NJ,, pp 257–290.

Manara A (2012) Plant responses to heavy metal toxicity. In: Furini A (ed) Plants and Heavy Metals: Springer Briefs in Molecular Science. Springer, New York, NY, pp 27–53.

Nesler A, Furini A (2012) Phytoremediation: the utilization of plants to reclaim polluted sites. In: Furini A (ed) Plants and Heavy Metals: Springer Briefs in Molecular Science. Springer, New York, NY, pp 75–86.

Twyman RM, Schillberg S, FIscher R (2012) The production of vaccines and therapeutic antibodies in plants. In: Ma S, Wang A (eds) Molecular Farming in Plants: Recent Advances and Future Prospects. Springer, Dordrecht, Netherlands, pp 145–159.

Farré G, Naqvi S, Sanahuja G, Bai C, Zorrilla-López U, Rivera SM, Canela R, Sandman G, Twyman RM, Capell T, Zhu C, Christou P (2011) Combinatorial genetic transformation of cereals and the creation of metabolic libraries for the carotenoid pathway. In: Dunwell J (ed) Transgenic Plants: Protocols and Methods. Methods in Molecular Biology 847. Humana Press, New York, NY, pp 419–435.

Gottschalk U (2011) Overview of downstream processing in the biomanufacturing industry. In: Moo-Young M, Butler M, Webb C, Moreira A, Grodzinski B, Cui ZF, Agathos S (eds) Comprehensive Biotechnology (Second Edition). Elsevier, Amsterdam, Netherlands, pp 669–682.

Tappe A, Gottschalk U (2011) Single-use downstream equipment. In: Eibl R, Eibl D (eds) Single-Use Technology in Biopharmaceutical Manufacture. John Wiley & Sons, Inc., Hoboken, NJ, pp 91–103.

Tornielli GB, Zamboni A, Zenoni S, Delledonne M, Pezzotti M (2011) Transcriptomics and metabolomics for the analysis of grape berry development. In: Gerós H, Chaves MM, Delrot S (eds) The Biochemistry of the Grape Berry. Bentham Science Publishers, Sharjah, UAE, pp 218–240.

Walter JK, Jin Z, Jornitz MW, Gottschalk U (2011) Membrane separations. In: Janson JC (ed) Protein Purification: Principles, High Resolution Methods, and Applications (Third Edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 279–317.

Kohli A, Miro B, Twyman RM (2010) Transgene integration, expression and stability in plants: strategies for improvements. In: Kole C, Michler CH, Abbott AG, Hall TC (eds) Biotech Plants, Volume 1: Concepts & Development. Springer, Berlin, Heidelberg, Germany, pp 201–238.

Schiermeyer A, Schillberg S (2010) Pharmaceuticals. In: Kempken F, Jung C (eds) Genetic Modification of Plants. Biotechnology in Agriculture and Forestry 64. Springer, New York, NY, pp 221–235.

Walter JK, Gottschalk U (2010) Concepts for disposables in biopharmaceutical manufacture. In: Shire SJ, Gombotz W, Bechtold-Peters K, Andya J (eds) Current Trends in Monoclonal Antibody Development and Manufacturing. Biotechnology: Pharmaceutical Aspects, Volume IX. Springer, New York, NY, pp 87–99.

Arunakumari A, Wang J (2009) Purification of human monoclonal antibodies: non-protein A strategies. In: Gottschalk U (ed) Process-scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 103–123.

Cabanne C, Santarelli X (2009) Purification of antibodies other than IgG: the case of IgM and IgA. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 373–386.

Christou P, Capell T (2009) Transgenic crops and their applications for sustainable agriculture and food security. In: Ferry N, Gatehouse AMR (eds) Environmental Impact of Genetically Modified Crops. CAB International, Wallingford, UK, pp 3–22.

Curling J (2009) The development of antibody purification technologies. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 25–52.

Etzel MR (2009) Charged ultrafiltration and microfiltration membranes in antibody purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 325–347.

Farid SS (2009) Process economic drivers in industrial monoclonal antibody manufacture. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 239–261.

Fischer R, Schillberg S, Twyman RM (2009) Molecular farming of antibodies in plants. In: Kirakosyan A, Kaufman PB (eds) Recent Advances in Plant Biotechnology. Springer, New York, NY, pp 35–63.

Fontes N, van Reis R (2009) Advances in technology and process development for industrial-scale monoclonal antibody purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 203–221.

Gagnon P (2009) Purification of monoclonal antibodies by mixed-mode chromatography. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 125–143.

Ghose S, Jin M, Liu J, Hickey J (2009) Integrated polishing steps for monoclonal antibody purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 145–167.

Glynn J (2009) Process-scale precipitation of impurities in mammalian cell culture broth. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 309–324.

Gottschalk U (2009) Disposables in downstream processing. In: Eibl R, Eibl D (eds) Disposable Bioreactors. Advances in Biochemical Engineering/Biotechnology 115. Springer, New York, NY, pp 171–183.

Kelley B, Blank G, Lee A (2009) Downstream processing of monoclonal antibodies: current practices and future opportunities. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 1–23.

Li Y, Kahn DW, Galperina O, Blatter E, Luo R, Wu Y, Zhang G (2009) Development of a platform process for the purification of therapeutic monoclonal antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 187–201.

Müller-Späth T, Morbidelli M (2009) Continuous chromatography for the purification of monoclonal antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 223–238.

Nikolov ZL, Regan JY, Dickey LF, Woodard SL (2009) Purification of antibodies from transgenic plants. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 387–406.

Pujar N, Low D, O'Leary R (2009) Antibody purification: drivers of change. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 407–426.

Ramessar K, Naqvi S, Dashevskaya S, Peremarti A, Yuan D, Gomez-Galera D, Velez SMR, Farre G, Sabalza M, Miralpeix B, Twyman RM, Zhu C, Bassie L, Capell T, Christou P (2009) The contribution of plant biotechnology to food security in the 21st century. In: Amsel L, Hirsch L (eds) Food Science and Security. Nova Science Publishers, New York, NY, pp 3–72.

Shukla AA, Kandula JR (2009) Harvest and recovery of monoclonal antibodies: cell removal and clarification. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 53–78.

Sinclair A (2009) Design and optimization of manufacturing. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 263–291.

Sparrow PAC, Twyman RM (2009) Biosafety and risk assessment of plant-made pharmaceuticals. In: Faye L, Gomord V (eds) Recombinant Pharmaceutical Proteins from Plants. Methods in Molecular Biology 483. Humana Press, New York, NY, pp 341–353.

Spitali M (2009) Downstream processing of monoclonal antibody fragments. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 349–372.

Thömmes J, Gottschalk U (2009) Alternatives to packed-bed chromatography for antibody extraction and purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 293–308.

Twyman RM (2009) Wnt pathway and neural patterning. In: Lemke G (ed) Developmental Neurobiology. Elsevier Press, Amsterdam, Netherlands, pp 39–44.

Twyman RM (2009) Transcriptional silencing. In: Lemke G (ed) Developmental Neurobiology. Elsevier Press, Amsterdam, Netherlands, pp 178–183.

Vunnum S, Vedantham G, Hubbard B (2009) Protein A-based affinity chromatography. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 79–102.

Zenoni S, Zamboni A, Porceddu A, Pezzotti M (2009) The role of expansins A in petunia development. In: Greats T, Strommer J (eds) Petunia. Springer, New York, NY, pp 247–267.

Zhou JX (2009) Orthogonal virus clearance applications in monoclonal antibody production. In: Gottschalk U (ed) Process Scale Purification of Antibodies. John Wiley & Sons, Inc., Hoboken, NJ, pp 169–186.

Fischer R, Twyman RM, Hellwig S, Drossard J, Schillberg S (2007) Facing the future with pharmaceuticals from plants. In: Xu Z, Li J, Xue Y, Yang W (eds) Biotechnology and Sustainable Agriculture 2006 and Beyond. Proceedings of the 11th IAPTC&B Congress, August 13-18, 2006 Beijing, China. Springer, New York, NY, pp 13–32.

Gottschalk U (2007) Downstream procesing. In: Jornitz MJ, Meltzer TH (eds) Filtration and Purification in the Biopharmaceutical Industry (Second Edition). Drugs and the Pharmaceutical Sciences 174. Informa Healthcare New York, NY/London, UK, pp 459–494.

Gottschalk U (2007) Downstream processing: removing economic and technical bottlenecks. In: Langer ES (ed) Advances in Large-Scale Biopharmaceutical Manufacturing and Scale-Up Production (Second Edition). BioPlan Associates Inc., Rockville MD/ASM Press, Washington DC, pp 913–948.

Twyman RM, Schillberg S, Fischer R (2007) Molecular farming of antibodies in plants. In: Ranalli P (ed) Improvements of Crop Plants for Industrial End Uses. Springer, Dordrecht, Netherlands, pp 435-469.

Twyman RM, Schillberg S, Fischer R (2006) Production of therapeutic antibodies in plants. In: Kayser O, Quax W (eds) Medicinal Plant Biotechnology: From Basic Research to Industrial Applications. Wiley-VCH Verlag GmbH, Weinheim, Germany, pp 319–344.

Zimmermann S, Emans N, Fischer R, Schillberg S (2006) Plantibody-based disease resistance in plants. In: Tuzun S, Bent E (eds) Multigenic and Induced Systemic Resistance in Plants. Springer, New York, NY, pp 456–476.

Christou P, Capell T (2005) Metabolic engineering in plants for food security. In: Tuberosa R, Phillips RL, Gale M (eds) In the Wake of the Double Helix: From the Green Revolution to the Gene Revolution. Avenue Media, Bologna, Italy, pp 545–557.

Fischer R, Twyman RM, Drossard J, Hellwig S, Schillberg S (2005) Plant cells. In: Gellissen G (ed) Production of Recombinant Proteins: Novel Microbial and Eukaryotic Expression Systems. Wiley-VCH Verlag GmbH, Weinheim, Germany, pp 253–272.

Schillberg S, Twyman RM, Fischer R (2005) Biopharmaceutical production in cultured plant cells. In: Knablein J (ed) Modern Biopharmaceuticals: Design, Development and Optimization. Wiley-VCH Verlag GmbH, Weinheim, Germany, pp 949–966.

Ammann K (2004) The role of science and discourse in the application of the precautionary approach. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 291–302.

Bischoff F (2004) A top-down view of molecular farming from the pharmaceutical industry: requirements and expectations. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 267–290.

Brandle J (2004) The field evaluation of transgenic crops engineered to produce recombinant proteins. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 69–76.

Chargelegue D, Drake PMW, Obregon P, Ma JKC (2004) Production of secretory IgA in transgenic plants. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 159–169.

Christou P, Stoger E, Twyman RM (2004) Monocot expression systems for molecular farming. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 55–67.

Commandeur U, Twyman RM (2004) Biosafety aspects of molecular farming in plants. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 251–266.

Daniell H, Carmona-Sanchez O, Burns BE (2004) Chloroplast derived antibodies, biopharmaceuticals and edible vaccines. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 113–133.

D'Aoust MA, Busse U, Martel M, Lerouge P, Levesque D, Vézina LP (2004) Perennial plants as a production system for pharmaceuticals. In: Christou P, Klee H (eds) Handbook of Plant Biotechnology. John Wiley & Sons, Inc., Hoboken, NJ, pp 759–767.

D'Aoust MA, Lerouge P, Busse U, Bilodeau P, Trépanier S, Gomord V, Faye L, Lou Vézina LP (2004) Efficient and reliable production of pharmaceuticals in alfalfa. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 1–12.

Drossard J (2004) Downstream processing of plant-derived recombinant therapeutic proteins. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 217–231.

Giersberg M, Saalbach I, Bäumlein H (2004) Gene farming in pea under field conditions. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 183–190.

Gomord V, Fitchette AC, Lerouge P, Faye L (2004) Glycosylation of plant-made pharmaceuticals. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 233–250.

Hood EE (2004) Plants as enzyme factories. In: Christou P, Klee H (eds) Handbook of Plant Biotechnology. John Wiley & Sons, Inc., Hoboken, NJ, pp 781–800.

Grill LK (2004) Production of pharmaceutical proteins using viral vectors. In: Christou P, Klee H (eds) Handbook of Plant Biotechnology. John Wiley & Sons, Inc., Hoboken, NJ, pp 781–789.

Khalsa G, Mason HS, Arntzen CJ (2004) Plant-derived vaccines: progress and constraints. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 135–158.

Koivu K (2004) Novel sprouting technology for recombinant protein production. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 37–53.

Komari T, Ishida U, Hiei Y (2004) Agrobacterium-mediated transformation. In: Christou P, Klee H (eds) Handbook of Plant Biotechnology. John Wiley & Sons, Inc., Hoboken, NJ, pp 233–261.

Mor TS, Mason HS (2004) Plants as a source for subunit vaccines. In: Christou P, Klee H (eds) Handbook of Plant Biotechnology. John Wiley & Sons, Inc., Hoboken, NJ, pp 769–780.

Scheller J, Conrad U (2004) Production of spider silk proteins in transgenic tobacco and potato. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 171–181.

Schiermeyer A, Dorfmüller S, Schinkel H (2004) Production of pharmaceutical proteins in plants and plant cell suspension cultures. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 91–112.

Schillberg S, Twyman RM (2004) Emerging production systems for antibodies in plants. In: Christou P, Klee H (eds) Handbook of Plant Biotechnology. John Wiley & Sons, Inc., Hoboken, NJ, pp 801–810.

Shadwick FS, Doran PM (2004) Foreign protein expression using plant cell suspension and hairy root cultures. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 13–36.

Stoger E, Marcel S, Twyman RM (2004) Crop plants for molecular farming. In: Christou P, Klee H (eds) Handbook of Plant Biotechnology. John Wiley & Sons, Inc., Hoboken, NJ, pp 747–758.

Stoger E, Schillberg S, Twyman RM, Fischer R, Christou P (2004) Antibody production in transgenic plants. In: Lo BKC (ed) Antibody Engineering: Protocols and Methods (Second Edition). Methods in Molecular Biology 248. Humana Press, New York, NY, pp 301–318.

Twyman RM (2004) Host plants, systems and expression strategies for molecular farming. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 191–216.

Twyman RM, Christou P (2004) Plant transformation technology – particle bombardment. In: Christou P, Klee H (eds) Handbook of Plant Biotechnology. John Wiley & Sons, Inc., Hoboken, NJ, pp 263–289.

Yusibov V, Rabindran S (2004) Plant viral expression vectors: history and new developments. In: Fischer R, Schillberg S (eds) Molecular Farming: Plant-made Pharmaceuticals and Technical Proteins. John Wiley & Sons, Inc., Hoboken, NJ, pp 77–90.

Fischer R, Emans NJ, Twyman RM, Schillberg S (2003) Molecular farming of industrial proteins in plants. In: Fingerman M, Nagabhushanam R (eds) Recent Advances in Marine Biotechnology, Volume 9 (Biomaterials and Bioprocessing). Science Publishers, Inc, Enfield, NH, pp 279–313.

Strachan T, Twyman RM (2003) Cells and development. In: Strachan T, Reid AP, Human Molecular Genetics 3. Garland Science, Abingdon, UK, pp 59–100.

Twyman RM (2003) Beyond the genome project: an introduction to functional genomics. In: Strachan T, Reid AP, Human Molecular Genetics 3. Garland Science, Abingdon, UK, pp 539–574.

Twyman RM (2003) Genetic modification of cells and animals. In: Strachan T, Reid AP, Human Molecular Genetics 3. Garland Science, Abingdon, UK, pp 575–608.

Sgouros JG, Twyman RM (2002) Gene finding. In: Orengo C, Jones DT, Thornton JM (eds) Bioinformatics: Genes, Proteins & Computers. BIOS Scientific Publishers, Oxford, UK, pp 18–28.

Twyman RM (2002) Building the body – the molecular basis of development. In: Sweeney S, Hodder D (eds) The Body (Darwin College Lectures). Cambridge University Press, Cambridge, UK, pp 12–24.

Twyman RM, Christou P, Stoger E (2002) Genetic transformation of plants and their cells. In: Oksman-Caldentey K-M, Barz W (eds) Plant Biotechnology and Transgenic Plants. Marcel Dekker, New York, NY, pp 111–141.

Twyman RM, Stoger E, Kohli A, Capell T, Christou P (2002) Selectable and screenable markers for rice transformation. In: Jackson JF, Linskens HF (eds) Testing for Genetic Manipulation in Plants. Molecular Methods of Plant Analysis 22. Springer, Berlin, Heidelberg, Germany, pp 1–17.

Twyman RM, Stoger E, Kohli A, Christou P (2002) Foreign DNA: integration and expression in transgenic plants. In: Setlow JK (ed) Genetic Engineering. Genetic Engineering: Principles and Methods 24. Springer, Boston, MA, pp 107–136.

Weir MP, Blackstock WP, Twyman RM (2002) Proteomics. In: Orengo C, Jones DT, Thornton JM (eds) Bioinformatics: Genes, Proteins & Computers. BIOS Scientific Publishers, Oxford, UK, pp 245–258.