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Description
Description
Description
Twyman
Research
Management Ltd
Description
Specialist consultants in scientific project development, management and presentation

Book Chapters, 2015-2018

 2018 and in press 

 

Fischer R, Holland T, Sack M, Schillberg S, Stoger E, Twyman RM, Buyel JF (2018) Glyco-engineering of plant-based expression systems. In: Rapp E, Reichl U (eds) Advances in Glycobiotechnology. Advances in Biochemical Engineering/Biotechnology. Springer, New York, NY (in press).

Holland T, Buyel JF (2018) Bioreactor-based production of glycoproteins in plant cell suspension cultures. In: Picanço-Castro V, Swiech K (eds) Recombinant Glycoprotein Production. Methods in Molecular Biology 1674. Humana Press, New York, NY, pp 129–146.  DOI

Hundleby PAC, Sack M, Twyman RM (2018) Biosafety, risk assessment and regulation of molecular farming. In: Kermode A, Fraser S, Jiang L (eds) Molecular Pharming: Applications, Challenges and Emerging Areas. Wiley-VCH Verlag GmbH, Mannheim, Germany (in press).

McElroy C, Jennewein S (2018) Taxol® biosynthesis and production: from forests to fermenters. In: Schwab W, Lange B, Wüst M (eds) Biotechnology of Natural Products. Springer International, Cham, Switzerland, pp 145–185.  DOI

Spiegel H, Stöger E, Twyman RM, Buyel JF (2018) Current status and perspectives of the molecular farming landscape. In: Kermode A, Fraser S, Jiang L (eds) Molecular Pharming: Applications, Challenges and Emerging Areas. Wiley-VCH Verlag GmbH, Mannheim, Germany (in press).


 2017 

Allen L (2017) The evolution of platform technologies for the downstream processing of antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 365–390.  DOI

Arunakumari A, Wang J (2017) Purification of human monoclonal antibodies: non-protein A strategies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 135–154.  DOI

Buyel JF (2017) How plants can contribute to the supply of anti-cancer compounds. In Malik S (ed) Biotechnology and Production of Anti-Cancer Compounds. Springer International, Cham, Switzerland, pp 39–72.  DOI

Buyel JF, Twyman RM, Fischer R (2017) Very-large-scale production of monoclonal antibodies in plants. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 655–672.  DOI

Chabanne C, Santarelli X (2017) Purification of IgM and IgA. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 615–630.  DOI

Curling J (2017) The development of antibody purification technologies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 23–54.  DOI

Elseberg C, Leber J, Weidner T, Czermak P (2017) The challenge of human mesenchymal stromal cell expansion: current and prospective answers. In Gowder SJT (ed) New Insights into Cell Culture Technology. InTech, Rijeka, Croatia, pp 99–134.  DOI

Etzel MR, Arunkumar A (2017) Charged ultrafiltration and microfiltration membranes for antibody purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 247–268.  DOI

Farid SS (2017) Process economic drivers in industrial monoclonal antibody manufacture. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 445–466.  DOI

Fontes N, Van Reis R (2017) Advances in technology and process development for industrial scale monoclonal antibody purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 199–214.  DOI

Gagnon P (2017) Purification of monoclonal antibodies by mixed mode chromatography. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 181–198.  DOI

Garonzi M, Centomo C, Delledonne M (2017) Next generation sequencing for next generation diagnostics and therapies. In Nadin M (ed) Anticipation and Medicine. Springer International, Cham, Switzerland, pp 87–102.  DOI

Ghose S, Jin M, Liu J, Hickey J, Lee S (2017) Integrated polishing steps for monoclonal antibody purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 303–324.  DOI

Glynn J (2017) Process-scale precipitation of impurities in mammalian cell culture broth. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 233–246.  DOI

Grein TA, Weidner T, Czermak P (2017) Concepts for the production of viruses and viral vectors in cell cultures. In Gowder SJT (ed) New Insights into Cell Culture Technology. InTech, Rijeka, Croatia, pp 173–192.  DOI

Hahn T, Huuk T, Hubbuch J (2017) High-throughput screening and modeling technologies for process development in antibody purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 515–536.  DOI

Kelley B (2017) Downstream processing of monoclonal antibodies: current practices and future opportunities. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 1–22.  DOI

Li Y, Zhu M, Luo H, Weaver JR (2017) Development of a platform process for the purification of therapeutic monoclonal antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 343–364.  DOI

Mahler H-C, Mathäs R (2017) Trends in formulation and drug delivery for antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 673–698.  DOI

Mothes B (2017) Accelerated seamless antibody purification: simplicity is key. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 431–444.  DOI

Müller-Späth T, Morbidelli M (2017) Continuous chromatography for the purification of monoclonal antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 391–408.  DOI

Nikolov ZL, Regan JT, Dickey LF, Woodard SL (2017) Purification of antibodies from plants. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 631–654.  DOI

Pujar N, Low D, O’Leary R (2017) Antibody purification: drivers of change. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 699–716.  DOI

Rohrer T (2017) Manufacturing concepts for antibody–drug conjugates. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 595–614.  DOI

Schillberg S, Raven N, Fischer R, Twyman RM, Schiermeyer A (2017) Contained molecular farming using plant cell and tissue cultures. In: Yoshida T (ed) Applied Bioengineering. Innovations and Future Directions. Wiley-VCH Verlag GmbH, Weinheim, Germany, pp 261281.  DOI 

Shukla AA, Norman CL (2017) Downstream processing of Fc fusion proteins, bispecific antibodies and antibody–drug conjugates. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 559–594.  DOI

Shukla AA, Suda E (2017) Harvest and recovery of monoclonal antibodies: cell removal and clarification. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 55–80.  DOI

Sinclair A (2017) Design and optimization of manufacturing. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 467–494.  DOI
Singh N, Chollangi S (2017) Next-generation clarification technologies for the downstream processing of antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 81–112.  DOI
Spitali M (2017) Downstream processing of monoclonal antibody fragments. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 537–558.  DOI

Thömmes J, Twyman RM, Gottschalk U (2017) Alternatives to packed-bed chromatography for antibody extraction and purification. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 215–232.  DOI

Tingley SK (2017) Disposable prepacked bed chromatography for downstream purification: form, fit, function and industry adoption. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 269–302.  DOI
Vajda J, Müller E (2017) Hydrophobic interaction chromatography for the purification of antibodies. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 155–180.  DOI
Vilcinskas A (2017) The impact of parasites on host insect epigenetics. In: Verlinden H (ed) Insect Epigenetics. Advances in Insect Physiology 53. Academic Press, London, UK, pp 145–165.  DOI

Vunnum S, Vedantham G, Hubbard B (2017) Protein A-based affinity chromatography. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 113–134.  DOI
Zhou JX (2017) Orthogonal virus clearance applications in monoclonal antibody production. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 325–342.  DOI
Zhou JX, Li J, Cui M, Chen H (2017) Smart design for an efficient facility with a validated disposable system. In: Gottschalk U (ed) Process Scale Purification of Antibodies (second edition). John Wiley & Sons, Inc., Hoboken, NJ, pp 495–514.  DOI

Zitzmann J, Sprick G, Weidner T, Schreiber C, Czermak P (2017) Process optimization for recombinant protein expression in insect cells. In Gowder SJT (ed) New Insights into Cell Culture Technology. InTech, Rijeka, Croatia, pp 43–97.  DOI


 2016 

Baudach AF, Mukherjee K (2016) Epigenetic control of polyphenism in aphids. In Vilcinskas A (ed) Biology and Ecology of Aphids. CRC Press, Boca Raton, FL, pp 89–99.  DOI

Bellin D, Delledonne M, Vandelle E (2016) Detection of peroxynitrite in plants exposed to bacterial infection. In Gupta KJ (ed) Plant Nitric Oxide Methods and Protocols. Methods in Molecular Biology 1424. Humana Press, New York, NY, pp 191–200.  DOI

Boes A, Reimann A, Twyman RM, Fischer R, Schillberg S, Spiegel H (2016) A plant-based transient expression system for the rapid production of malaria vaccine candidates. In Thomas S (ed) Vaccine Design Methods and Protocols, Volume 2 Vaccines for Veterinary Diseases. Methods in Molecular Biology 1404. Humana Press, New York, NY, pp 597619.  DOI

Peschen D, Schillberg S, Fischer R (2016) Antibody-mediated pathogen resistance in plants. In MacDonald J, Kolotilin I, Menassa R (eds) Recombinant Proteins from Plants. Methods in Molecular Biology 1385. Humana Press, New York, NY, pp 273–291.  DOI

Skaljac M (2016) Bacterial symbionts of aphids (Hemiptera: Aphididae). In Vilcinskas A (ed) Biology and Ecology of Aphids. CRC Press, Boca Raton, FL, pp 100–125.  DOI

Vilcinskas A (2016) Aphid immunity. In Vilcinskas A (ed) Biology and Ecology of Aphids. CRC Press, Boca Raton, FL, pp 126–134.  DOI

Vilcinskas A, Schmidtberg H (2016) The ontogenesis of the pea aphid Acyrthosiphon pisum. In Vilcinskas A (ed) Biology and Ecology of Aphids. CRC Press, Boca Raton, FL, pp 14–51.  DOI

Will T (2016) Aphid techniques. In Vilcinskas A (ed) Biology and Ecology of Aphids. CRC Press, Boca Raton, FL, pp 255–270.  DOI


 2015 

 

Cremer C, Hehmann-Titt G, Schiffer S, Melmer G, Carloni P, Barth S, Nachreiner T (2015) Engineered versions of granzyme B and angiogenin overcome intrinsic resistance to apoptosis mediated by human cytolytic fusion proteins. In: Verma RS, Bonavida B (eds) Resistance to Immunotoxins in Cancer Therapy. Resistance to Targeted Anti-Cancer Therapeutics Volume 6. Springer International, Cham, Switzerland, pp 185–219.  DOI


For earlier book chapters we have helped to prepare, please click here

 


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