Description
Description
Description
Description
Twyman
Research
Management Ltd
Description
Specialist consultants in scientific project development, management and presentation

Research Articles, 2015-2018

 2018 and in press 

 

Agu HO, Hameed A, Appleby-Thomas GJ (2018) Application of shell jetting analysis to determine the location of the virtual origin in shaped charges. Int J Impact Eng 122, 175–181.  DOI 


Baudach A, Lee KZ, Vogel H, Vilcinskas A (2018) Immunological larval polyphenism in the map butterfly Araschnia levana reveals the photoperiodic modulation of immunity. Ecol Evol 8 (10) 4891–4898.  DOI


Beinecke FA, Grundmann L, Wiedmann DR, Schmidt FJ, Caesar AS, Zimmermann M, Lahme M, Twyman RM, Prüfer D, Noll GA (2018) The FT/FD-dependent initiation of flowering under long-day conditions in the day-neutral species Nicotiana tabacum originates from the facultative short-day ancestor N. tomentosiformis. Plant J 96 (2) 329–342.  DOI

Bertini E, Merlin M, Gecchele E, Puggia A, Brozzetti A, Commisso M, Falorni A, Bini V, Klymyuk V, Pezzotti M, Avesani L (2018) Design of a type-1 diabetes vaccine candidate using edible plants expressing a major autoantigen. Front Plant Sci  9, 572.  DOI 

Bhuvanachandra B, Madhuprakash J, Podile AR (2018) Active-site mutations improved the transglycosylation activity of Stenotrophomonas maltophilia chitinase A. Biochim Biophys Acta 1866 (3) 407–414.  DOI


Bröker JN, Müller B, van Deenen N, Prüfer D, Schulze Gronover C (2018) Upregulating the mevalonate pathway and repressing sterol synthesis in Saccharomyces cerevisiae enhances the production of triterpenes. Appl Microbiol Biotechnol 102 (16) 6923–6934.  DOI


Carrau T, Hiebert N, Vilcinskas A, Lee KZ (2018) Isolation and characterization of natural viruses associated with the invasive insect pest Drosophila suzukii. J Invertebr Pathol 154, 74–78.  DOI


Chew SC, Tennant M, Mai N, McAteer D, Pons JF (2018) Practical remediation of 3-nitro-1,2,4-triazol-5-one wastewater. Prop Expl Pyrotech 43 (2) 198–202.  DOI


Dal Santo S, Zenoni S, Sandri M, De Lorenzis G, Magris G, De Paoli E, Di Gaspero G, Del Fabbro C, Morgante M, Brancadoro L, Grossi D, Fasoli M, Zuccolotto P, Tornielli GB, Pezzotti M (2018) Grapevine field experiments reveal the contribution of genotype, the influence of environment and the effect of their interaction (G×E) on the berry transcriptome. Plant J 93 (6) 1143–1159.  DOI


Dossi E, Akhavan J, Gaulter SE, Williams RG, Doe WJ (2018) Cross-linking of hydroxyl-terminated polyols with triethyleneglycol diglycidyl ether: an alternative to toxic isocyanates. Prop Expl Pyrotech 43 (3) 241–250.  DOI


Ebrahimi M, Kerker S, Schmitz O, Schmidt AA, Czermak P (2018) Evaluation of the fouling potential of ceramic membrane configurations designed for the treatment of oilfield produced water. Sep Sci Technol 53 (2) 349–363.  DOI


Ehirim OH, Knowles K, Saddington AJ, Finnis MV (2018) Aerodynamics of a convex shaped bump on a ground-effect effect diffuser. J Fluids Eng 140 (9) 091102.  DOI


Fasoli M, Richter CL, Zenoni S, Bertini E, Vitulo N, Dal Santo S, Dokoozlian N, Pezzotti M, Tornielli GB (2018) Timing and order of the molecular events marking the onset of berry ripening in grapevine. Plant Physiol (online first).  DOI 


Fernández-Colino A, Wolf F, Rütten S, Rodríguez-Cabello JC, Jockenhoevel S, Mela P (2018) Combining catalyst-free click chemistry with coaxial electrospinning to obtain long-term, water-stable, bioactive elastin-like fibers for tissue engineering applications. Macromol Biosci (online first).  DOI 


Gengenbach BB, Müschen CR, Buyel JF (2018) Expression and purification of human phosphatase and actin regulator 1 (PHACTR1) in plant-based systems. Protein Expr Purif 151, 46–55.  DOI


Gegner T, Schmidtberg H, Vogel H, Vilcinskas A (2018) Population-specific expression of antimicrobial peptides conferring pathogen resistance in the invasive ladybird Harmonia axyridis. Sci Rep 8 (1) 3600.  DOI


Gehring C, Welle F (2018) Migration testing of polyethylene terephthalate: comparison of regulated test conditions with migration into real food at the end of shelf life. Pack Tech Sci (online first).  DOI


Gonçalves S, Medronho J, Moreira E, Grosso C, Andrade PB, Valentão P, Romano A (2018) Bioactive properties of Chamaerops humilis L.: antioxidant and enzyme inhibiting activities of extracts from leaves, seeds, pulp and peel. 3 Biotech 8 (2) 88.  DOI


Grein TA, Loewe D, Dieken H, Weidner T, Salzig D, Czermak P (2018) High titer oncolytic measles production process by integration of dielectric spectroscopy as online monitoring system. Biotechnol Bioeng 15 (5) 1186–1194.  DOI


Gresch G, Schenke L, Mladenov R, Zwirner S, Cremer C, Niesen J, Grieger E, Brümmendorf T, Jost E, Fischer R, Stockmeyer B, Barth S, Nachreiner T, Stein C (2018) Elimination of different leukaemia subtypes using novel CD89-specific human cytolytic fusion proteins. Br J Haematol (online first).  DOI


Hausmann R, Chudobová I, Spiegel H, Schillberg S (2018) Proteomic analysis of CHO cell lines producing high and low quantities of a recombinant antibody before and after selection with methotrexate. J Biotechnol 265, 65–69.  DOI


Hirsch R, Wiesner J, Marker A, Bauer A, Hammann PE, Vilcinskas A (2018) Biological profiling of coleoptericins and coleoptericin-Like antimicrobial peptides from the invasive harlequin ladybird Harmonia axyridis. Adv Exp Med Biol (online first).  DOI


Hirsch R, Wiesner J, Marker A, Pfeifer Y, Bauer A, Hammann PE, Vilcinskas A (2018) Profiling antimicrobial peptides from the medical maggot Lucilia sericata as potential antibiotics for MDR Gram-negative bacteria. J Antimicrob Chemother (online first).  DOI


Hoffmann S, Gorzelanny C, Moerschbacher BM, Goycoolea FM (2018) Physicochemical characterization of FRET-labelled chitosan nanocapsules and model degradation studies. Preprints 2018090318 (online first)DOI


Jansing J, Buyel JF (2018) The correlation between DsRed mRNA levels and transient DsRed protein expression in plants depends on leaf age and the 5' untranslated region. J Biotechnol (online first).  DOI


Jansing J, Sack M, Augustine S, Fischer R, Bortesi L (2018) CRISPR/Cas9-mediated knockout of six glycosyltransferase genes in Nicotiana benthamiana for the production of recombinant proteins lacking beta-1,2-xylose and core alpha-1,3-fucose. Plant Biotechnol J (online first).  DOI


Kalagara T, Moutsis T, Yang Y, Pappelbaum KI, Farken A, Cladder-Micus L, Vidal-Y-Sy S, John A, Bauer AT, Moerschbacher BM, Schneider SW, Gorzelanny C (2018) The endothelial glycocalyx anchors von Willebrand factor fibers to the vascular endothelium. Blood Adv 2 (18) 2347–2357.  DOI


Kechagias-Stamatis O, Aouf N (2018) A new passive 3D automatic target recognition architecture for aerial platforms. IEEE Trans Geosci Rem Sens (online first).  DOI


Laibach N, Schmidl S, Müller B, Bergmann M, Prüfer D, Schulze Gronover C (2018) Small rubber particle proteins from Taraxacum brevicorniculatum promote stress tolerance and influence the size and distribution of lipid droplets and artificial poly(cis-1,4-isoprene) bodies. Plant J 93 (6) 1045–1061.  DOI


Lindner M, Höflsauer F, Heider J, Reinelt M, Langowski HC (2018) Comparison of thickness determination methods for physical-vapor-deposited aluminum coatings in packaging applications. Thin Solid Films 666, 6–14.  DOI


Luppi F, Cavaye H, Dossi E (2018) Nitrated cross-linked ß-cyclodextrin binders exhibiting low glass transition temperatures. Prop Expl Pyrotech (online first).  DOI


Masola V, Zaza G, Bellin G, Dall'Olmo L, Granata S, Vischini G, Secchi MF, Lupo A, Gambaro G, Onisto M (2018) Heparanase regulates the M1 polarization of renal macrophages and their crosstalk with renal epithelial tubular cells after ischemia/reperfusion injury. FASEB J 32 (2) 742–756.  DOI


Melnik S, Neumann AC, Karongo R, Dirndorfer S, Stübler M, Ibl V, Niessner R, Knopp D, Stoger E (2018) Cloning and plant-based production of antibody MC10E7 for a lateral flow immunoassay to detect [4-arginine]microcystin in fresh water. Plant Biotechnol J 16 (1) 27–38.  DOI


Menghiu G, Ostafe V, Prodanovic R, Fischer R, Ostafe R (2018) Biochemical characterization of chitinase A from Bacillus licheniformis DSM8785 expressed in Pichia pastoris KM71H. Protein Expr Purif 154, 25–32.  DOI


Menzel S, Holland T, Boes A, Spiegel H, Fischer R, Buyel JF (2018) Downstream processing of a plant-derived malaria transmission-blocking vaccine candidate. Protein Expr Purif 152, 122–130.  DOI


Mukherjee K, Grizanova E, Chertkova E, Lehmann R, Dubovskiy I, Vilcinskas A (2018) Experimental evolution of resistance against Bacillus thuringiensis in the insect model host Galleria mellonella results in epigenetic modifications. Virulence 8 (8) 1618–1630.  DOI 


Mukherjee K, Vilcinskas A (2018) The entomopathogenic fungus Metarhizium robertsii communicates with the insect host Galleria mellonella during infection. Virulence 9 (1) 401–413.  DOI


Nölke G, Barsoum M, Houdelet M, Arcalís E, Kreuzaler F, Fischer R, Schillberg S (2018) The integration of algal carbon concentration mechanism components into tobacco chloroplasts increases photosynthetic efficiency and biomass. Biotechnol J (online first).  DOI 


Nölke G, Volke D, Chudobova I, Houdelet M, Lusso M, Frederick J, Adams A, Kudithipudi C, Warek U, Strickland JA, Xu D, Schinkel H, Schillberg S (2018) Polyamines delay leaf maturation in low-alkaloid tobacco varieties. Plant Direct 2 (7) e00077.  DOI


Pérez L, Soto E, Villorbina G, Bassie L, Medina V, Muñoz P, Capell T, Zhu C, Christou P, Farré G (2018) CRISPR/Cas9-induced monoallelic mutations in the cytosolic AGPase large subunit gene APL2 induce the ectopic expression of APL2 and the corresponding small subunit gene APS2b in rice leaves. Transgenic Res 27 (5) 423–439.  DOI


Ramakrishna B, Vaikuntapu P, Mallakuntla MK, Bhuvanachandra B, Sivaramakrishna D, Uikey S, Podile AR (2018) Carboxy-terminal glycosyl hydrolase 18 domain of a carbohydrate active protein of Chitinophaga pinensis is a non-processive exochitinase. Int J Biol Macromol 115, 1225–1232.  DOI


Röder J, Dickmeis C, Fischer R, Commandeur U (2018) Systemic infection of Nicotiana benthamiana with Potato virus X nanoparticles presenting a fluorescent iLOV polypeptide fused directly to the coat protein. BioMed Res Int 2018, 9328671.  DOI


Rodríguez-Solana R, Galego LR, Pérez-Santín E, Romano A (2018) Production method and varietal source influence the volatile profiles of spirits prepared from fig fruits (Ficus carica L.) Eur Food Res Technol 244 (12) 2213–2229.  DOI

Rühl C, Knödler M, Opdensteinen P, Buyel JF (2018) A linear epitope coupled to DsRed provides an affinity ligand for the capture of monoclonal antibodies as an alternative to Protein A. J Chromatogr A 1571, 55–64.  DOI


Schlich K, Hoppe M, Kraas M, Schubert J, Chanana M, Hund-Rinke K (2018) Long-term effects of three different silver sulfide nanomaterials, silver nitrate and bulk silver sulfide on soil microorganisms and plants. Environ Pollut 242 part B, 1850–1852.  DOI


Shukla SP, Plata C, Reichelt M, Steiger S, Heckel DG, Kaltenpoth M, Vilcinskas A, Vogel H (2018) Microbiome-assisted carrion preservation aids larval development in a burying beetle. Proc Natl Acad Sci USA (online first).  DOI


Skaljac M, Kirfel P, Grotmann J, Vilcinskas A (2018) Fitness costs of infection with Serratia symbiotica are associated with greater susceptibility to insecticides in the pea aphid Acyrthosiphon pisum. Pest Manag Sci 74 (9) 1829–1836.  DOI 


Tello G, Al-Jarrah OY, Yoo PD, Al-Hammadi Y, Muhaidat S, Lee U (2018) Deep-structured machine learning model for the recognition of mixed-defect patterns in semiconductor fabrication processes. IEEE Trans Semicond Manufact 31 (2) 315–322.  DOI 


Temple T, Ladyman M, Mai N, Galante E, Ricamora M, Shirazi R, Coulon F (2018) Investigation into the environmental fate of the combined insensitive high explosive constituents 2,4-dinitroanisole (DNAN), 1-nitroguanidine (NQ) and nitrotriazolone (NTO) in soil. Sci Total Env 625, 1264–1271.  DOI


Unland K, Pütter K, Vorwerk K, van Deenen N, Twyman RM, Prüfer D, Schulze Gronover C (2018) Functional characterization of squalene synthase and squalene epoxidase in Taraxacum koksaghyz. Plant Direct 2 (6) e00063.  DOI


Vaikuntapu PR, Mallakuntla MK, Das SN, Bhuvanachandra B, Ramakrishna B, Nadendla SR, Podile AR (2018) Applicability of endochitinase of Flavobacterium johnsoniae with transglycosylation activity in generating long-chain chitooligosaccharides. Int J Biol Macromol 117, 62–71.  DOI

Vamvaka E, Farré G, Molinos-Albert LM, Evans A, Canela-Xandri A, Twyman RM, Carrillo J, Ordóñez RA, Shattock RJ, O’Keefe BR, Clotet B, Blanco J, Khush GS, Christou P, Capell T (2018) Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm. Proc Natl Acad Sci USA 115 (33) E7854–E7862.  DOI

Vogel H, Müller A, Heckel DG, Gutzeit H, Vilcinskas A (2018) Nutritional immunology: Diversification and diet-dependent expression of antimicrobial peptides in the black soldier fly Hermetia illucens. Dev Comp Immunol 78, 141–148.  DOI


Wall DG, Economou J, Knowles K (2018) Quasi-real-time confined environment path generation for mobile robotic manipulator arms. J Sys Control Eng 232 (3) 270–284.  DOI 


Wollschlaeger C, Meinhold-Heerlein I, Cong X, Braeutigam K, Di Fiore S, Zeppernick F, Klockenbring T, Stickeler E, Barth S, Hussain AF (2018) Simultaneous and independent dual site-specific self-labeling of recombinant antibodies. Bioconjug Chem (online first).  DOI


Wong DCJ, Ariani P, Castellarin S, Polverari A, Vandelle E (2018) Co-expression network analysis and cis-regulatory element enrichment determine putative functions and regulatory mechanisms of grapevine ATL E3 ubiquitin ligases. Sci Rep 8 (1) 3151.  DOI


Zitzmann J, Schreiber C, Eichmann J, Bilz RO, Salzig D, Weidner T, Czermak P (2018) Single-cell cloning enables the selection of more productive Drosophila melanogaster S2 cells for recombinant protein expression. Biotechnol Rep 19, e00272.  DOI


Zitzmann J, Weidner T, Eichner G, Salzig D, Czermak P (2018) Dielectric spectroscopy and optical density measurement for the online monitoring and control of recombinant protein production in stably transformed Drosophila melanogaster S2 cells. Sensors 18 (3) 900.  DOI 



 2017 


Amsel D, Vilcinskas A, Billion A (2017) Evaluation of high-throughput isomiR identification tools: illuminating the early isomiRome of Tribolium castaneum. BMC Bioinformatics 18 (1) 359.  DOI


Bai C, Capell T, Sandmann G, Christou P, Zhu C (2017) Reconstruction of the astaxanthin biosynthesis pathway in rice endosperm reveals a metabolic bottleneck at the level of endogenous ß-carotene hydroxylase activity in rice endosperm. Transgenic Res 26 (1) 13–23.  DOI


Banakar R, Alvarez Fernández Á, Abadía J, Capell T, Christou P (2017) The expression of heterologous Fe (III) phytosiderophore transporter HvYS1 in rice increases Fe uptake, translocation and seed loading and excludes heavy metals by selective Fe transport. Plant Biotechnol J 15 (4) 423–432.  DOI


Banakar R, Alvarez Fernandez A, Díaz-Benito P, Abadia J, Capell T, Christou P (2017) Phytosiderophores determine thresholds for iron and zinc accumulation in biofortified rice endosperm while inhibiting the accumulation of cadmium. J Exp Bot 68 (17) 4983–4995.  DOI


Bauerschlag D, Meinhold-Heerlein I, Maass N, Bleilevens A, Bräutigam K, Al Rawashdeh W, Di Fiore S, Haugg AM, Gremse F, Steitz J, Fischer R, Stickeler E, Barth S, Hussain AF (2017) Detection and specific elimination of EGFR+ ovarian cancer cells using a near infrared photoimmunotheranostic approach. Pharm Res 34 (4) 696–703.  DOI 


Baumann A, Skaljac M, Lehmann R, Vilcinskas A, Franta Z (2017) Urate oxidase produced by Lucilia sericata medicinal maggots is localized in Malpighian tubes and facilitates allantoin production. Insect Biochem Mol Biol 83, 44–53.  DOI


Berges N, Arens K, Kreusch V, Fischer R, Di Fiore S (2017) Toward discovery of novel microtubule targeting agents: A SNAP-tag-based high-content screening assay for the analysis of microtubule dynamics and cell cycle progression. SLAS Discov 22 (4) 387–398.  DOI


Berman J, Zorrilla-López U, Medina V, Farré G, Sandmann G, Capell T, Christou P, Zhu C (2017) The Arabidopsis thaliana ORANGE (AtOR) gene promotes carotenoid and ketocarotenoid accumulation in transgenic corn hybrids derived from parental lines with limited carotenoid pools. Plant Cell Rep 36 (6) 933–945.  DOI


Berman J, Zorrilla-López U, Sandmann G, Capell T, Christou P, Zhu C (2017) The silencing of carotenoid ß-hydroxylases by RNA interference in different maize genetic backgrounds increases the ß-carotene content of the endosperm. Int J Mol Sci 18 (12) 2515.  DOI


Bingsohn L, Knorr E, Billion A, Narva KE, Vilcinskas A (2017) Knockdown of genes in the Toll pathway reveals new lethal RNAi targets for insect pest control. Insect Mol Biol 26 (1) 92102.  DOI


Bolouri Moghaddam MR, Gross T, Becker A, Vilcinskas A, Rahnamaeian M (2017) The selective antifungal activity of Drosophila melanogaster metchnikowin reflects the species-dependent inhibition of succinate-coenzyme Q reductase. Sci Rep 7 (1) 8192.  DOI

Bolouri Moghaddam MR, Vilcinskas A, Rahnamaeian M (2017) The insect-derived antimicrobial peptide metchnikowin targets Fusarium graminearum ß(1,3) glucanosyltransferase Gel1, which is required for the maintenance of cell wall integrity. Biol Chem 398 (4) 491–498.  DOI

Busse N, Kraume M, Czermak P (2017) Modeling the design and operational mode of a continuous membrane reactor for enzymatic lignin modification. Biochem Eng J 124, 88–98.  DOI


Buyel JF, Gruchow H, Wehner M (2017) A rapid laser probing method facilitates the non-invasive and contact-free determination of leaf thermal properties. J Vis Exp (119) e54835.  DOI  


Camiolo S, Sablok G, Porceddu A (2017) The evolutionary basis of translational accuracy in plants. G3 (Bethesda) 7 (7) 2363–2373.  DOI


Chouman K, Woitok M, Mladenov R, Kessler C, Weinhold E, Hanz G, Fischer R, Meinhold-Heerlein I, Bleilevens A, Gresch G, Haugg AM, Zeppernick F, Bauerschlag D, Maass N, Stickeler E, Kolberg K, Hussain AF (2017) Fine tuning antibody conjugation methods using SNAP-tag technology. Anti-Cancer Agents Med Chem 17 (10) 1434–1440.  DOI


Commisso M, Anesi A, Dal Santo S, Guzzo F (2017) Performance comparison of electrospray ionization and atmospheric pressure chemical ionization in untargeted and targeted liquid chromatography/mass spectrometry based metabolomics analysis of grapeberry metabolites. Rapid Commun Mass Spec 31 (3) 292–300.  DOI


Commisso M, Bianconi M, Di Carlo F, Poletti S, Bulgarini A, Munari F, Negri S, Stocchero M, Ceoldo S, Avesani L, Assfalg M, Zoccatelli G, Guzzo F (2017) Multi-approach metabolomics analysis and artificial simplified phytocomplexes reveal cultivar-dependent synergy between polyphenols and ascorbic acid in fruits of the sweet cherry (Prunus avium L). PLOS One 12 (7) e0180889.  DOI


Denk P, Buettner A (2017) Sensory characterization and identification of odorous constituents in acrylic adhesives. Int J Adhesion Adhesives 78, 182–188.  DOI


Díaz-Gómez J, Moreno JA, Angulo E, Sandmann G, Zhu C, Ramos AJ, Capell T, Christou P, Nogareda C (2017) High-carotenoid biofortified maize is an alternative to color additives in poultry feed. Animal Feed Sci Technol 231, 38–46.  DOI


Ece S, Lambertz C, Fischer R, Commandeur U (2017) Heterologous expression of a Streptomyces cyaneus laccase for biomass modification applications. AMB Express 7, 86.  DOI


Ehlicke F, Köster N, Salzig D, Czermak P (2017) Non-invasive Raman spectroscopy and quantitative real-time PCR distinguish among undifferentiated human mesenchymal stem cells and redifferentiated nucleus pulposus cells and chondrocytes in vitro. Open Biomed Eng J 11, 72–84.  DOI


Fan R, Ebrahimi M, Czermak P (2017) Anaerobic membrane bioreactor for continuous lactic acid fermentation. Membranes 7 (2) 26.  DOI


Fan R, Ebrahimi M, Quitmann H, Czermak P (2017) Lactic acid production in a membrane bioreactor system with thermophilic Bacillus coagulans: online monitoring and process control using an optical sensor. Separation Sci Technol 52 (2) 352–363.  DOI


Fang X, Sharma M, Stennett C, Gill PP (2017) Optical sensitisation of energetic crystals with gold nanoparticles for laser ignition. Combust Flame 183, 15–21.  DOI


Fasani E, DalCorso G, Varotto C, Li M, Visioli G, Mattarozzi M, Furini A (2017) The MTP1 promoters from Arabidopsis halleri reveal cis-regulating elements for the evolution of metal tolerance. New Phytol 214 (4) 1614–1630.  DOI


Gorchs G, Lloveras L, Serranoa L, Celab S (2017) Hemp yields and its rotation effects on wheat under rainfed Mediterranean conditions. Agron J 109 (4) 1551–1560.  DOI


Grau T, Vilcinskas A, Joop G (2017) Probiotic Enterococcus mundtii isolate protects the model insect Tribolium castaneum against Bacillus thuringiensis. Front Microbiol 8, 1261.  DOI


Grein TA, Schwebel F, Kress M, Loewe D, Dieken H, Salzig D, Weidner T, Czermak P (2017) Screening different host cell lines for the dynamic production of Measles virus. Biotechnol Prog 33 (4) 989–997.  DOI


Grieger E, Gresch G, Niesen J, Woitok M, Barth S, Fischer R, Fendel R, Stein C (2017) Efficient targeting of CD13 on cancer cells by the immunotoxin scFv13-ETA' and the bispecific scFv [13xds16]. J Cancer Res Clin Oncol 143 (11) 2159–2170.  DOI


Havenith H, Kern K, Rautenberger P, Spiegel H, Szardenings M, Ueberham E, Lehmann J, Buntru M, Vogel S, Treudler R, Fischer R, Schillberg S (2017) Combination of two epitope identification techniques enables the rational design of soy allergen Gly m 4 mutants. Biotechnol J 12 (2) 1600441.  DOI


Heitmueller M, Billion A, Dobrindt U, Vilcinskas A, Mukherjee K (2017) Epigenetic mechanisms regulate innate immunity against uropathogenic and commensal-like Escherichia coli in the surrogate insect model Galleria mellonella. Infect Immunol 85 (10) e00336-17.  DOI

Hoppe M, Fornari R, de Voogt P, Franz R (2017) Migration of oligomers from PET: determination of diffusion coefficients and comparison of experimental versus modelled migration. Food Addit Contam A 34 (7) 1251–1260.  DOI

Houdelet M, Galinski A, Holland T, Wenzel K, Schillberg S, Buyel JF (2017) Animal component-free Agrobacterium tumefaciens cultivation media for better GMP compliance increases biomass yield and pharmaceutical protein expression in Nicotiana benthamiana. Biotechnol J 12 (4) 1600721.  DOI

Hu H, Zhang Y, Shukla S, Gu Y, Yu X, Steinmetz NF (2017) Dysprosium-modified Tobacco mosaic virus nanoparticles for ultra-high-field magnetic resonance and near-infrared fluorescence imaging of prostate cancer. ACS Nano 11 (9) 9249–9258.  DOI

Kapusi E, Corcuera-Gomes M, Melnik S, Stoger E (2017) Heritable genomic fragment deletions and small indels in the putative ENGase gene induced by CRISPR/Cas9 in barley. Front Plant Sci 8, 540.  DOI 

Kastilan R, Boes A, Spiegel H, Voepel N, Chudobová I, Hellwig S, Buyel JF, Reimann A, Fischer R (2017) Improvement of a fermentation process for the production of two PfAMA1-DiCo-based malaria vaccine candidates in Pichia pastoris. Sci Rep 7 (1) 11991.  DOI

Kiese S, Kücükpinar E, Reinelt M, Miesbauer O, Ewender J, Langowski HC (2017) A systematic approach for the accurate and rapid measurement of water vapor transmission through ultra-high barrier films. Rev Sci Instrum 88 (2) 025108.  DOI

Kirchhoff KN, Hauffe T, Stelbrink B, Albrecht C, Wilke T (2017) Evolutionary bottlenecks in brackish water habitats drive the colonization of fresh water by stingrays. J Evol Biol 30 (8) 1576–1591.  DOI 

Klose D, Woitok M, Niesen J, Beerli RR, Grawunder U, Fischer R, Barth S, Fendel R, Nachreiner T (2017) Generation of an artificial human B cell line test system using Transpo-mAb™ technology to evaluate the therapeutic efficacy of novel antigen-specific fusion proteins. PLOS One 12 (7) e0180305.  DOI

Knappich F, Schlummer M, Hartl F, Mäurer A (2017) Complete recycling of composite material comprising polybutylene terephthalate and copper. Recycling 2 (2) 9.  DOI

Kumar M, Ladyman MK, Mai N, Temple T, Coulon F (2017) Release of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) from polymer-bonded explosives (PBXN-109) into water by artificial weathering. Chemosphere 169, 604–608.  DOI

Leber J, Barekzai J, Blumenstock M, Pospisil B, Salzig D, Czermak P (2017) Microcarrier choice and bead-to-bead transfer for human mesenchymal stem cells in serum-containing and chemically defined media. Process Biochem 59 (B) 225–265.  DOI

Lee KZ, Vilcinskas A (2017) Analysis of virus susceptibility in the invasive insect pest Drosophila suzukii. J Invertebr Pathol 148, 138–141.  DOI

Ling T, Bellin D, Vandelle E, Imanifard Z, Delledonne M (2017) Host-mediated S-nitrosylation disarms the bacterial effector HopAI1 to reestablish immunity. Plant Cell 29 (11) 2871–2881.  DOI

Luna-Ramirez K, Miller AD, Rašic G (2017) Genetic and morphological analyses indicate that the Australian endemic scorpion Urodacus yaschenkoi (Scorpiones: Urodacidae) is a species complex. PeerJ 5, e2759.  DOI

Luna-Ramirez K, Skaljac M, Grotmann J, Kirfel P, Vilcinskas A (2017) Orally delivered scorpion antimicrobial peptides exhibit activity against pea aphid (Acyrthosiphon pisum) and its bacterial symbionts. Toxins (Basel) 9 (9) 261.  DOI

Luna-Ramirez K, Tonk M, Rahnamaeian M, Vilcinskas A (2017) Bioactivity of natural and engineered antimicrobial peptides from venom of the scorpions Urodacus yaschenkoi and U. manicatus. Toxins (Basel) 9 (1) 22.  DOI

Martínez E, Maresma A, Biau A, Berenguer P, Cela S, Santiveri F, Michelena A, Lloveras J (2017) Long-term effects of pig slurry combined with mineral nitrogen on maize in a Mediterranean irrigated environment. Field Crops Res 214, 341–349.  DOI

Martínez E, Maresma A, Biau A, Cela S, Berenguer P, Santiveri F, Michelena A, Lloveras J (2017) Long-term effects of mineral nitrogen fertilizer on irrigated maize and soil properties. Agronomy J 109 (5) 1880–1890.  DOI

Masarapu H, Patel BK, Chariou PL, Hu H, Gulati NM, Carpenter BL, Ghiladi RA, Shukla S, Steinmetz NF (2017) Physalis mottle virus-like particles as nanocarriers for imaging reagents and drugs. Biomacromolecules 18 (12) 4141–4153.  DOI

Massonnet M, Fasoli M, Tornielli GB, Altieri M, Sandri M, Zuccolotto P, Paci P, Gardiman M, Zenoni S, Pezzotti M (2017) Ripening transcriptomic program in red and white grapevine varieties correlates with berry skin anthocyanin accumulation. Plant Physiol 174 (4) 2376–2396.  DOI

Menegon M, Cantaloni C, Rodriguez-Prieto A, Centomo C, Abdelfattah A, Rossato M, Bernardi M, Xumerle L, Loader S, Delledonne M (2017) On-site DNA barcoding by nanopore sequencing. PLOS One 12 (10) e0184741.  DOI

Mercenaro L, Nieddu G, Porceddu A, Pezzotti M, Camiolo S (2017) Sequence polymorphisms and structural variations among four grapevine (Vitis vinifera L.) cultivars representing Sardinian agriculture. Front Plant Sci 8, 1279.  DOI

Mukherjee K, Grizanova E, Chertkova E, Lehmann R, Dubovskiy I, Vilcinskas A (2017) Experimental evolution of resistance against Bacillus thuringiensis in the insect model host Galleria mellonella results in epigenetic modifications. Virulence 8 (8) 1618–1630.  DOI

Negri S, Lovato A, Boscaini F, Salvetti E, Torriani S, Commisso M, Danzi R, Ugliano M, Polverari A, Tornielli GB, Guzzo F (2017) The induction of noble rot (Botrytis cinerea) infection during postharvest withering changes the metabolome of grapevine berries (Vitis vinifera L., cv. Garganega). Front Plant Sci 8, 1002.  DOI

Nesler A, DalCorso G, Fasani E, Manara A, Di Sansebastiano GP, Argese E, Furini A (2017) Functional components of the bacterial CzcCBA efflux system reduce cadmium uptake and accumulation in transgenic tobacco plants. New Biotechnol 35, 54–61.  DOI

Oppermann T, Busse N, Czermak P (2017) Mannheimia haemolytica growth and leukotoxin production for vaccine manufacturing – a bioprocess review. Elec J Biotechnol 28, 95–100.  DOI

Özdemir S, Heerd D, Quitmann H, Zhang Y, Fraatz MA, Zorn H, Czermak P (2017) Process parameters affecting the synthesis of natural flavors by shiitake (Lentinula edodes) during the production of a non-alcoholic beverage. Beverages 3 (2) 20.  DOI

Pant AF, Sängerlaub S, Müller K (2017) Gallic acid as an oxygen scavenger in bio-based multilayer packaging films. Materials  10 (5) 489.  DOI 

Pusceddu M, Floris I, Buffa F, Salaris E, Satta A (2017) Agonistic interactions between the honeybee (Apis mellifera ligustica) and the European wasp (Vespula germanica) reveal context-dependent defense strategies. PLOS One 12 (7) e0180278.  DOI

Pütter KM, van Deenen N, Unland K, Prüfer D, Schulze Gronover C (2017) Isoprenoid biosynthesis in dandelion latex is enhanced by the overexpression of three key enzymes involved in the mevalonate pathway. BMC Plant Biol 17 (1) 88.  DOI

Röder J, Fischer R, Commandeur U (2017) Adoption of the 2A ribosomal skip principle to Tobacco mosaic virus for peptide display. Front Plant Sci 8, 1125.  DOI

Röder J, Fischer R, Commandeur U (2107) Engineering Potato virus X particles for a covalent protein based attachment of enzymes. Small 13 (48) 1702151.  DOI

Schott M, Bischoff G, Eichner G, Vilcinskas A, Büchler R, Meixner MD, Brandt A (2017) Temporal dynamics of whole body residues of the neonicotinoid insecticide imidacloprid in live or dead honeybees. Sci Rep 7(1) 6288.  DOI

Schreiber C, Müller H, Birrenbach O, Klein M, Heerd D, Weidner T, Salzig D, Czermak P (2017) A high-throughput expression screening platform to optimize the production of antimicrobial peptides. Microbial Cell Fact 16 (1) 29.  DOI

Shiratori H, Feinweber C, Luckhardt S, Linke B, Resch E, Geisslinger G, Weigert A, Parnham MJ (2017) THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitro. Mol Immunol 88, 58–68.  DOI

Sonnack L, Klawonn T, Kriehuber R, Hollert H, Schäfers C, Fenske M (2017) Concentration dependent transcriptome responses of zebrafish embryos after exposure to cadmium, cobalt and copper. Comp Biochem Physiol Part D Genomics Proteomics 24, 29–40.  DOI

Spiegel H, Boes A, Fendel R, Reimann A, Schillberg S, Fischer R (2017) Immunization with the malaria diversity-covering blood-stage vaccine candidate Plasmodium falciparum Apical Membrane Antigen 1 DiCo in complex with its natural ligand PfRon2 does not improve the in vitro efficacy. Front Immunol 8, 743.  DOI

Sprick G, Weidner T, Salzig D, Czermak P (2017) Baculovirus-induced recombinant protein expression in human mesenchymal stromal stem cells: a promoter study. New Biotechnol 39 (B) 161–166.  DOI

Stolze A, Wanke A, van Deened N, Greyer R, Prüfer D, Schulze Gronover C (2017) Development of rubber-enriched dandelion varieties by metabolic engineering of the inulin pathway. Plant Biotechnol J 15 (6) 740–753.  DOI

Vandelle E, Puttilli MR, Chini A, Devescovi G, Venturi V, Polverari A (2017) Application of chemical genomics to plant–bacteria communication: a high-throughput system to identify novel molecules modulating the induction of bacterial virulence genes by plant signals. Methods Mol Biol 1610, 297–314.  DOI

Vilcinskas A, Vogel H (2017) Seasonal phenotype-specific transcriptional reprogramming during metamorphosis in the European map butterfly Araschnia levana. Ecol Evol 6 (11) 34763485.  DOI

Vogel H, Schmidtberg H, Vilcinskas A (2017) Comparative transcriptomics of three ladybird species supports a role for immunity in invasion biology. Dev Comp Immunol 67, 452–456.  DOI

Vogel H, Shukla SP, Engl T, Weiss B, Fischer R, Steiger S, Heckel DG, Kaltenpoth M, Vilcinskas A (2017) The digestive and defensive basis of carcass utilization by the burying beetle and its microbiota. Nature Commun 8, 15186.  DOI

Weidner T, Druzinec D, Mühlmann M, Buchholz R, Czermak P (2017) The components of shear stress affecting insect cells used with the baculovirus expression vector system. Z Naturforsch C 72 (9–10) 429–439.  DOI

Will T, Schmidtberg H, Vilcinskas A (2017) Heat shock protein 83 plays pleiotropic roles in embryogenesis, longevity and fecundity in the pea aphid Acyrthosiphon pisum. Dev Genes Evo 227 (1) 1–9.  DOI

Woitok M, Klose D, Di Fiore S, Richter W, Stein C, Gresch G, Grieger E, Barth S, Fischer R, Kolberg K, Niesen J (2017) Comparison of a mouse and a novel human scFv-SNAP-auristatin F drug conjugate with potent activity against EGFR-overexpressing human solid tumor cells. Onco Targets Ther 10, 3313–3327.  DOI

Zitzmann J, Weidner T, Czermak P (2017) Optimized expression of the antimicrobial peptide gloverin from Galleria mellonella using stably transformed Drosophila melanogaster S2 cells. Cytotechnology 69 (2) 371–379.  DOI

Zheng Z, Tharmalingam N, Liu Q, Jayamani E, Kim W, Fuchs BB, Zhang R, Vilcinskas A, Mylonakis E (2017) The synergistic efficacy of Aedes aegypti antimicrobial peptide cecropin A2 and tetracycline against Pseudomonas aeruginosa. Antimicrob Agents Chemother 61, e00686-17.  DOI


 2016 

 

Addai-Mensah O, Seidel M, Amidu N, Maskus DJ, Kapelski S, Breuer G, Franken C, Owusu-Dabo E, Frempong M, Rakotozandrindrainy R, Schinkel H, Reimann A, Klockenbring T, Barth S, Fischer R, Fendel R (2016) Acquired immune responses to three malaria vaccine candidates and their relationship to invasion inhibition in two populations naturally exposed to malaria. Malaria J 15 (1) 65.  DOI


Allegro G, Pastore C, Valentini G, Muzzi E, Filippetti I (2016) Influence of berry ripeness on accumulation, composition and extractability of skin and seed flavonoids in cv. Sangiovese (V. vinifera L). J Sci Food Agric 96 (13) 4553–4559.  DOI


Amoury M, Bauerschlag D, Zeppernick F, von Felbert V, Berges N, Di Fiore S, Mintert I, Bleilevens A, Maass N, Bräutigam K, Meinhold-Heerlein I, Stickeler E, Barth S, Fischer R, Hussain AF (2016) Photoimmunotheranostic agents for triple-negative breast cancer diagnosis and therapy that can be activated on demand. Oncotarget 7 (34) 54925–54936.  DOI


Andreolli M, Lampis S, Brignoli P, Vallini G (2016) Trichoderma longibrachiatum Evx1 is a fungal biocatalyst suitable for the remediation of soils contaminated with diesel fuel and polycyclic aromatic hydrocarbons. Environ Sci Pollut Res Int 23 (9) 9134–9143.  DOI


Andreolli M, Lampis S, Zapparoli G, Angelini E, Vallini G (2016) Diversity of bacterial endophytes in 3 and 15 year-old grapevines of Vitis vinifera cv. Corvina and their potential for plant growth promotion and phytopathogen control. Microbiol Res 183, 42–52.  DOI


Arfi ZA, Hellwig S, Drossard J, Fischer R, Buyel JF (2016) Polyclonal antibodies for the specific detection of tobacco host cell proteins can be generated more efficiently following RuBisCO depletion and the removal of endotoxins. Biotechnol J 11 (4) 507–518.  DOI


Ariani P, Regaiolo A, Lovato A, Giorgetti A, Porceddu A, Camiolo S, Wong D, Castellarin S, Vandelle E, Polverari A (2016) Genome-wide characterisation and expression profile of the grapevine ATL ubiquitin ligase family reveal biotic and abiotic stress-responsive and development-related members. Sci Rep 6, 38260.  DOI 


Bai C, Capell T, Berman J, Medina V, Sandmann G, Christou P, Zhu C (2016) Bottlenecks in carotenoid biosynthesis and accumulation in rice endosperm are influenced by the precursor–product balance. Plant Biotechnol J 14 (1) 195–205.  DOI

Baysal C, Bortesi L, Zhu C, Farré G, Schillberg S, Christou P (2016) CRISPR/Cas9 activity in the rice OsBEIIb gene does not induce off-target effects in the closely related paralog OsBEIIa. Mol Breeding 36, 108.  DOI

Beckert A, Wiesner J, Schmidtberg H. Lehmann R, Baumann A, Vogel H, Vilcinskas A (2016) Expression and characterization of a recombinant i-type lysozyme from the harlequin ladybird beetle Harmonia axyridis. Insect Mol Biol 25 (3) 202–215.  DOI

Berman J, Sheng Y, Gomez Gomez L, Veiga T, Ni X, Farré G, Capell T, Guitián J, Guitián P, Sandmann G, Christou P, Zhu C (2016) Red anthocyanins and yellow carotenoids form the color of orange-flower gentian (Gentiana lutea var. aurantiaca).  PLOS One 11 (9) e0162410.  DOI 

Bialon M, Grezella C, Schellenberg L, Sieben T, Pham AT, Fischer R, Barth S, Püttmann C, Stein C (2016) A monoclonal antibody that discriminates between SNAP-tagged and CLIP-tagged proteins. Monoclon Antib Immunodiagn Immunother  35 (3) 141–147.  DOI

Bingsohn L, Knorr E, Vilcinskas A (2016) The model beetle Tribolium castaneum can be used as an early-warning system for transgenerational epigenetic effects caused by pharmaceuticals. Comp Biochem Biophys 185–186, 57–64.  DOI

Boes A, Spiegel H, Kastilan R, Bethke S, Voepel N, Chudobová I, Bolscher JM, Dechering KJ, Fendel R, Buyel J, Reimann A, Schillberg S, Fischer R (2016) Analysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail. Malaria J 15 (1) 279.  DOI

Busse N, Fuchs F, Kraume M, Czermak P (2016) Treatment of enzyme initiated delignification reaction mixtures with ceramic ultrafiltration membranes - experimental investigations and modeling approach. Separation Sci Technol 51 (9) 15467–1565.  DOI

Buyel JF (2016) Numeric simulation can be used to predict heat transfer during the blanching of leaves and intact plants. Biochem Eng J (109) 118–126.  DOI

Buyel JF (2016) Procedure to evaluate the efficiency of flocculants for the removal of dispersed particles from plant extracts. J Vis Exp (110) e53940.  DOI

Buyel JF, Gruchow HM, Fischer R (2016) Depth filters containing diatomite achieve more efficient particle retention than filters solely containing cellulose fibers. Front Plant Sci 6, 1134.  DOI

Buyel JF, Gruchow HM, Tödter N, Wehner M (2016) Determination of the thermal properties of leaves by non-invasive contact-free laser probing. J Biotechnol 217, 100–108.  DOI

Buyel JF, Hubbuch J, Fischer R (2016) Comparison of tobacco host cell protein removal methods by blanching intact plants or by heat treatment of extracts. J Vis Exp (114) e54343.  DOI

Camiolo S, Melito S, Porceddu A (2016) New insights into the interplay between codon bias determinants in plants. DNA Res 22 (6) 461–470.  DOI

Commisso M, Toffali K, Strazzer P, Stocchero M, Ceoldo S, Baldan B, Levi M, Guzzo F (2016) Impact of phenylpropanoid compounds on heat stress tolerance in carrot cell cultures. Front Plant Sci 7, 1439.  DOI

Costa MP, Feitosa ACS, Oliveira FCE, Cavalcanti BC, da Silva EN, Dias GG, Sales FAM, Sousa BL, Barroso-Neto IL, Pessoa C, Caetano EWS,  Di Fiore S , Fischer R, Ladeira LO, Freire VN (2016) Controlled release of nor-ß-lapachone by PLGA microparticles: a strategy for improving cytotoxicity against prostate cancer cells. Molecules 21 (7) 873.  DOI

Cremonini E, Zonaro E, Donini M, Lampis S, Boaretti M, Dusi S, Melotti P, Lleo MM, Vallini G (2016) Biogenic selenium nanoparticles: characterization, antibacterial antimicrobial activity and effects on human dendritic cells and fibroblasts. Microb Boitechnol 9 (6) 758–771.  DOI

Dal Santo S, Commisso M, D’Incà E, Anesi A, Stocchero M, Zenoni S, Ceoldo S, Tornielli GB, Pezzotti M, Guzzo F (2016) The terroir concept interpreted through grape berry metabolomics and transcriptomics. J Vis Exp (116) e54410.  DOI

Dal Santo S, Fasoli M, Negri S, D’Incà E, Vicenzi N, Guzzo F, Tornielli GB, Pezzotti M, Zenoni S (2016) Plasticity of the berry ripening program in a white grape variety. Front Plant Sci 7, 970.  DOI

Dal Santo S, Palliotti A, Zenoni S, Tornielli GB, Fasoli M, Paci P, Tombesi S, Frioni T, Silvestroni O, Bellincontro A, d'Onofrio C, Matarese F, Gatti M, Poni S, Pezzotti M (2016) Distinct transcriptome responses to water limitation in isohydric and anisohydric grapevine cultivars. BMC Genom 17 (1) 815.  DOI


Damm T, Spiegel H, Barth S, Fischer R, Naehring J (2016) Development of a cystatin C specific bioassay for integration into an implantable biochip system. PLOS One 11 (1) e0147177.  DOI


de Bruin NMWJ, Schmitz K, Schiffmann S, Tafferner N, Schmidt M, Jordan H, Häußler A, Tegeder I, Geisslinger G, Parnham MJ (2016) Multiple rodent models and behavioral measures reveal unexpected responses to FTY720 and DMF in experimental autoimmune encephalomyelitis. Behav Brain Res 300, 160–174.  DOI


Degenkolb T Götze L, von Döhren H, Vilcinskas A, Brückner H (2016) Sequences of stilboflavin C: Towards the peptaibiome of the filamentous fungus Stilbella (=Trichoderma) flavipes. J Peptide Sci 22 (8) 517–524.  DOI


Deidda A, Buffa F, Linaldeddu BT, Pinna C, Scanu B, Deiana V, Satta A, Franceschini A, Floris I (2016) Emerging pests and diseases threaten Eucalyptus camaldulensis plantations in Sardinia, Italy. iForest 9, 883–891.  DOI


Ebrahimi M, Busse N, Kerker S, Schmitz O, Hilpert M, Czermak P (2016) Treatment of the bleaching effluent from sulfite pulp production by ceramic membrane filtration. Membranes 6 (1) 7.  DOI 


Elía M, Savin R, Slafer GA (2016) Fruiting efficiency in wheat: physiological aspects and genetic variation among modern cultivars. Field Crops Res 191, 83–90.  DOI


Eritja N, Arjo G, Santacana M, Gatius S, Ramírez-Núnez O, Arcal L, Serrano JCE, Pamplona R, Dolcet X, Piñol C, Christou P, Matias-Guiu X, Portero-Otín M (2016) Oral intake of genetically engineered high-carotenoid corn ameliorates hepatomegaly and hepatic steatosis in PTEN haploinsufficient mice. Biochim Biophys Acta 1862 (4) 526–535.  DOI


Fan R, Ebrahimi M, Quitmann H, Aden M, Czermak P (2016) An innovative optical sensor for the online monitoring and control of biomass concentration in a membrane bioreactor system for lactic acid production. Sensors 16 (3) 411.  DOI


Fasoli M, Dell'Anna R, Dal Santo S, Balestrini R, Sanson A, Pezzotti M, Monti F, Zenoni S (2016) Pectins, hemicelluloses and celluloses show specific dynamics in the internal and external surfaces of grape berry skin during ripening. Plant Cell Physiol 57 (6) 1332–1349.  DOI


Franta Z, Vogel H, Lehmann R, Rupp O, Goesmann A, Vilcinskas A (2016) Next generation sequencing identifies five major classes of potentially therapeutic enzymes secreted by Lucilia sericata medical maggots. BioMed Res Int 2016, 8285482.  DOI


Fritsch L, Soeur R, Hansen C, Fischer R, Schillberg S,  Schröper F (2016) Next-generation sequencing of amplicons is a rapid and reliable method for the detection of polymorphisms relevant for barley breeding. Mol Breeding 36, 83.  DOI


Fuenzalida JP, Nareddy PK, Moreno-Villoslada I, Moerschbacher BM, Swamy MJ, Pan S, Ostermeier M, Goycoolea FM (2016) On the role of alginate structure in complexing with lysozyme and application for enzyme delivery. Food Hydrocoll 53, 239–248.  DOI


Gaida SM, Liedtke A, Jentges AH, Engels B, Jennewein S (2016) Metabolic engineering of Clostridium cellulolyticum for the production of n-butanol from crystalline cellulose. Microb Cell Fact 15 (1) 6.  DOI


Grein TA, Leber J, Blumenstock M, Petry F, Weidner T, Salzig D, Czermak P (2016) Multiphase mixing characteristics in a microcarrier-based stirred tank bioreactor suitable for human mesenchymal stem cell expansion. Process Biochemistry 51 (9) 1109–1119.  DOI


Hoang KP, Teo TM, Ho TX, Le VS (2016) Mechanisms of sex determination and transmission ratio distortion in Aedes aegypti. Parasites & Vectors 9, 49.  DOI


Hofbauer A, Melnik S, Tschofen M, Arcalis E, Phan HT, Gresch U, Lampel J, Conrad U, Stoger E (2016) The encapsulation of hemagglutinin in protein bodies achieves a stronger immune response in mice than the soluble antigen. Front Plant Sci 7, 142.  DOI


Hristodorov D, Mladenov R, Fischer R, Barth S, Thepen T (2016) Fully-human MAP-fusion protein selectively targets and eliminates proliferating CD64+ M1 macrophages. Immunol Cell Biol 94 (5) 470478.  DOI


Hussain J, Chen J, Locato V, Sabetta W, Behera S, Cimini S, Griggio F, Martínez-Jaime S, Graf A, Bouneb M, Pachaiappan R, Fincato P, Blanco E, Costa A, De Gara L, Bellin D, Concetta de Pinto M, Vandelle E (2016) Constitutive cyclic GMP accumulation in Arabidopsis thaliana compromises systemic acquired resistance induced by an avirulent pathogen by modulating local signals. Sci Rep 6, 36423.  DOI


Jacobs CGC, Steiger S, Heckel DG, Vilcinskas A, Vogel H (2016) Sex, offspring and carcass determine antimicrobial peptide expression in the burying beetle. Sci Rep 6, 25409.  DOI  


Joop G, Vilcisnlkas A (2016) Coevolution of parasitic fungi and insect hosts. Zoology 119 (4) 350358.  DOI


Klose D, Saunders U, Barth S, Fischer R, Jacobi AM, Nachreiner T (2016) Novel fusion proteins for the antigen-specific staining and elimination of B cell receptor-positive cell populations demonstrated by a tetanus toxoid fragment C (TTC) model antigen. BMC Biotechnol 16 (1) 18.  DOI


Köster N, Schmiermund A, Grubelnig S, Leber J, Ehlicke F, Czermak P, Salzig D (2016) Single-step RNA extraction from in different hydrogels embedded mesenchymal stem cells for quantitative RT-PCR analysis. Tissue Eng Part C 22 (6) 552560.  DOI


Lambertz C, Eckert C, Fischer R, Commandeur U (2016) Kluyveromyces lactis as an expression host for enzymes that degrade lignocellulosic biomass. Cellulose Chem Tech 50 (34) 385389.  DOI

Manara A, DalCorso G, Furini A (2016) The role of the atypical kinases ABC1K7 and ABC1K8 in abscisic acid responses. Front Plant Sci 7, 366.  DOI


Manara A, DalCorso G, Guzzo F, Furini A (2016) Loss of the atypical kinases ABC1K7 and ABC1K8 changes the lipid composition of the chloroplast membrane. Plant Cell Physiol 56 (6) 11931204.  DOI


Melcher RLG, Moerschbacher BM (2016) An improved microtiter plate assay to monitor the oxidative burst in monocot and dicot plant cell suspension cultures. Plant Methods 12, 5.  DOI  


Menzel S, Holland T, Boes A, Spiegel H, Fischer R, Buyel JF (2016) Optimized blanching reduces the host cell protein content and substantially enhances the recovery and stability of two plant-derived malaria vaccine candidates. Front Plant Sci 7, 159.  DOI


Merlin M, Gecchele E, Arcalis E, Remelli S, Brozzetti A, Pezzotti M, Avesani L (2016) Enhanced GAD65 production in plants using the MagnICON transient expression system: optimization of upstream production and downstream processing. Biotechnol J 11 (4) 542–553.  DOI


Mladenov R, Hristodorov D, Cremer C, Gresch G, Grieger E, Schenke L, Klose D, Amoury M, Woitok M, Jost E, Brümmendorf TH, Fendel R, Fischer R, Stein C, Thepen T, Barth S (2016) CD64-directed microtubule associated protein tau kills leukaemic blasts ex vivo. Oncotarget 7 (41) 6716667174.  DOI


Moghaddam MRB, Tonk M, Schreiber C, Salzig D, Czermak P, Vilcinskas A, Rahnamaeian M (2016) The potential of the Galleria mellonella innate immune system is maximized by the co-presentation of diverse antimicrobial peptides. Biol Chem 397 (9) 939945.  DOI


Moreno JA, Díaz-Gómez J, Nogareda C, Angulo E, Sandmann G, Portero-Otin M, Serrano JCE, Twyman RM, Capell T, Zhu C, Christou P (2016) The distribution of carotenoids in hens fed on biofortified maize is influenced by feed composition, absorption, resource allocation and storage. Sci Rep 6, 35346.  DOI


Movahed N, Pastore C, Cellini A, Allegro G, Valentini G, Zenoni S, Cavallini E, D'Incà E, Tornielli GB, Filippetti I (2016) The grapevine VviPrx31 peroxidase as a candidate gene involved in anthocyanin degradation in ripening berries under high temperature. J Plant Res 129 (3) 513526.  DOI


Niesen J, Hehmann-Titt G, Woitok M, Fendel R, Barth S, Fischer R, Stein C (2016) A novel fully-human cytolytic fusion protein based on granzyme B shows in vitro cytotoxicity and ex vivo binding to solid tumors overexpressing the epidermal growth factor receptor. Cancer Lett 374 (2) 229–240.  DOI


Niesen J, Sack M, Seidel M, Fendel R, Barth S, Fischer R, Stein C (2016) SNAP-tag technology: a useful tool to determine affinity constants and other functional parameters of novel antibody fragments. Bioconjug Chem 27 (8) 1931–1941.  DOI


Nogareda C, Moreno JA, Angulo E, Sandmann G, Portero M, Capell T, Zhu C, Christou P (2016) Carotenoid-enriched corn delivers bioavailable carotenoids to poultry and protects them against coccidiosis. Plant Biotechnol J 14 (1) 97–108.  DOI


Pitek AS, Wen AM, Shukla S, Steinmetz NF (2016) The protein corona of plant virus nanoparticles influences their dispersion properties, cellular interactions, and in vivo fates. Small 12 (13) 1758–1769.  DOI 


Pöppel AK, Kahl M, Baumann A, Wiesner J, Gökçen A, Beckert A, Preissner KT, Vilcinskas A, Franta Z (2016) A Jonah-like chymotrypsin from the therapeutic maggot Lucilia sericata plays a role in wound debridement and coagulation. Insect Biochem Mol Biol 70, 138–147.  DOI


Rahnamaeian M, Cytrynska M, Zdybicka-Barabas A, Vilcinskas A (2016) The functional interaction between abaecin and pore-forming peptides indicates a general mechanism of antibacterial potentiation. Peptides 78, 17–23.  DOI


Rasche S, Herwartz D, Schuster F, Fischer R, Schillberg S (2016) More for less: Improving the biomass yield of a pear cell suspension culture by design of experiments. Sci Rep 6, 23371.  DOI


Salzig D, Leber J, Merkewitz K, Lange MC, Köster N, Czermak P (2016) Attachment, growth and detachment of human mesenchymal stem cells in a chemically defined medium. Stem Cells Int 2016, 5246584.  DOI


Schlich K, Beule L, Hund-Rinke K (2016) Single versus repeated applications of CuO and Ag nanomaterials and their effect on soil microflora. Env Poll 215, 322–330.  DOI


Schneider K, Schiermeyer A, Dolls A, Koch N, Herwartz D, Kirchhoff J, Fischer R, Russell SM, Cao Z, Corbin DR, Sastry-Dent L, Ainley WM, Webb SR, Schinkel H, Schillberg S (2016) Targeted gene exchange in plant cells mediated by a zinc finger nuclease double cut. Plant Biotechnol J 14 (4) 1151–1160.  DOI


Shiratori H, Feinweber C, Knothe C, Lötsch J, Geisslinger G, Resch E, Parnham M (2016) High-throughput analysis of global DNA methylation using methyl-sensitive digestion. PLOS One 11 (10) e0163184.  DOI


Spohner SC, Czermak P (2016) Heterologous expression of Aspergillus terreus fructosyltransferase in Kluyveromyces lactis. New Biotechnol 33 (4) 473–479.  DOI


Sreekanth KV, Alapan Y, ElKabbash M, Ilker E, Hinczewski M, Gurkan UA, De Luca A, Strangi G (2016) Extreme sensitivity biosensing platform based on hyperbolic metamaterials. Nature Materials 15, 621–627.  DOI


Tafferner N, Barthelmes J, Eberle M, Ferreiros N, Ulshöfer T, Henke M, deBruin N, Mayer CA, Foerch C, Geisslinger G, Parnham MJ, Schiffmann S (2016) Alpha-methylacyl-CoA racemase deletion has mutually counteracting effects on T-cell responses, associated with unchanged course of EAE. Eur J Immunol 46 (3) 570–581.  DOI


Ur Rehman A, Kovacs Z, Ebrahimi M, Quitmann H, Czermak P (2016) Enzymatic production of fructo-oligosaccharides from inexpensive and abundant substrates using a membrane reactor system. Separation Sci Technol 51 (9) 1537–1545.  DOI

Vaas LAI, Witt G, Windshügel B, Bosin A, Serra G, Bruengger A, Winterhalter M, Gribbon P, Levy-Petelinkar CJ, Kohler M (2016) Electronic laboratory notebooks in a public–private partnership. PeerJ Comp Sci 2, e83.  DOI

Vamvaka E, Arcalis E, Ramessar K, Evans A, O’Keefe BR, Shattock RJ, Medina V, Stoger E, Christou P, Capell T (2016) Rice endosperm is cost-effective for the production of recombinant griffithsin with potent activity against HIV. Plant Biotechnol J 14 (6) 1427–1437.  DOI

Vamvaka E, Evans A, Ramessar K, Krumpe LR, Shattock RJ, O’Keefe BR, Christou P, Capell T (2016) Cyanovirin-N produced in rice endosperm offers effective pre-exposure prophylaxis against HIV-1BaL infection in vitro. Plant Cell Rep 35 (6) 1309–1319.  DOI

Vamvaka E, Twyman RM, Murad AM, Melnik S, Teh AYH, Arcalis E, Altmann F, Stoger E, Rech E, Ma JKC, Christou P, Capell T (2016) Rice endosperm produces an underglycosylated and potent form of the HIV-neutralizing monoclonal antibody 2G12. Plant Biotechnol J 14 (1) 97–108.  DOI

Vasilev N, Boccard J, Lang G, Grömping U, Fischer R, Goepfert S, Rudaz S, Schillberg S (2016) Structured plant metabolomics for the simultaneous exploration of multiple factors. Sci Rep 6, 37390.  DOI

Visser F, Müller B, Rose J, Prüfer D, Noll GA (2016) Forizymes – functionalised artificial forisomes as a platform for the production and immobilisation of single enzymes and multi-enzyme complexes. Sci Rep 6, 30839.  DOI

Wiesner J, Hintz M, Reichenberg A, Ortmann R, Schlitzer M, Ziemann C, Fuhst R, Vilcinskas A, Jomaa H (2016) FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity. Virulence 7 (6) 718–728.  DOI 

Woitok M, Klose D, Niesen J, Richter W, Abbas M, Stein C, d, Fendel R, Bialon M, Püttmann C, Fischer R, Barth S, Kolberg K (2016) The efficient elimination of solid tumor cells by EGFR-specific and HER2-specific scFv-SNAP fusion proteins conjugated to benzylguanine-modified auristatin F. Cancer Lett 381 (2) 323330.  DOI

Zanga D, Capell T, Zhu C, Christou P, Thangaraj H (2016) Freedom-to-operate analysis of a transgenic multivitamin corn variety. Plant Biotechnol J 14 (5) 1225–1240.  DOI

Zanga D, Capell T, Slafer GA, Christou P, Savin R (2016) A carotenogenic mini-pathway introduced into white corn does not affect development or agronomic performance. Sci Rep 6, 38288.  DOI

Zenoni S, Fasoli M, Guzzo F, Dal Santo S, Amato A, Anesi A, Commisso M, Herderich M, Ceoldo S, Avesani L, Pezzotti M, Tornielli GB (2016) Disclosing the molecular basis of the postharvest life of berry in different grapevine genotypes. Plant Physiol 172 (3) 18211843.  DOI



 2015 

 

Abdellatef E, Will T, Koch A, Imani J, Vilcinskas A, Kogel KH (2015) Silencing the expression of the salivary sheath protein causes transgenerational feeding suppression in the aphid Sitobion avenae. Plant Biotechnol J 13 (6) 849–857.  DOI


Anesi A, Stocchero M, Dal Santo S, Commisso M, Zenoni S, Ceoldo S, Tornielli GB, Siebert TE, Herderich M, Pezzotti M, Guzzo F (2015) Towards a scientific interpretation of the terroir concept: plasticity of the grape berry metabolome. BMC Plant Biol 15, 191.  DOI

Baumann A, Lehmann R, Beckert A, Vilcinskas A, Franta Z (2015) Selection and evaluation of tissue specific reference genes in Lucilia sericata during an immune challenge. PLOS One 10 (8) e0135093.  DOI

Beckert A, Wiesner J, Baumann A, Pöppel AK, Vogel H, Vilcinskas A (2015) Two c-type lysozymes boost the innate immune system of the invasive ladybird Harmonia axyridis. Dev Comp Immunol 49 (2) 303–312.  DOI


Beiss V, Spiegel H, Boes A, Kapelski S, Scheuermayer M, Edgue G, Sack M, Fendel R, Reimann A, Schillberg S, Pradel G, Fischer R (2015) Heat-precipitation allows the efficient purification of a functional plant-derived malaria transmission-blocking vaccine candidate fusion protein. Biotechnol Bioeng 112 (7) 1297–1305.  DOI


Boes A, Spiegel H, Edgue G, Kapelski S, Scheuermayer M, Fendel R, Remarque E, Altmann F, Maresch D, Reimann A, Pradel G, Schillberg S, Fischer R (2015) Detailed functional characterization of glycosylated and nonglycosylated variants of malaria vaccine candidate PfAMA1 produced in Nicotiana benthamiana and analysis of growth inhibitory responses in rabbits. Plant Biotechnol J 13 (2) 222–234.  DOI


Boes A, Spiegel H, Voepel N, Edgue G, Beiss V, Kapelski S, Scheuermayer M, Pradel G, Bolscher JM, Behet MC, Dechering KJ, Hermsen CC, Sauerwein RW, Schillberg S, Reimann A, Fischer R (2015) Analysis of a multi-component multi-stage malaria vaccine candidate – tackling the cocktail challenge. PLOS One 10 (7) e0131456.  DOI

Brehm H, Hristodorov D, Pardo A, Mladenov R, Niesen J, Fischer R, Tur MK, Barth S (2015) Targeted killing of rhabdomyosarcoma cells by a MAP-based human cytolytic fusion protein. Cancer Lett 365 (2) 149–155.  DOI

Bruckman MA, Randolph LN, Gulati NM, Stewart PL, Steinmetz NF (2015) Silica-coated Gd(DOTA)-loaded protein nanoparticles enable magnetic resonance imaging of macrophages. J Mater Chem B 2015 (3) 7503–7510.  DOI

Buntru M, Vogel S, Stoff K, Spiegel H, Schillberg S (2015) A versatile coupled cell-free transcription-translation system based on tobacco BY-2 cell lysates. Biotechnol Bioeng 112 (5) 867–878.  DOI


Buyel JF (2015) Controlling the interplay between Agrobacterium tumefaciens and plants during the transient expression of proteins. Bioengineered 6 (4) 242–244.  DOI


Buyel JF, Buyel JJ, Hasse C, Fischer R (2015) The impact of Pseudomonas syringae type III effectors on transient protein expression in tobacco. Plant Biol 17 (2) 484492.  DOI


Buyel JF, Fischer R (2015) A juice extractor can simplify the downstream processing of plant-derived biopharmaceutical proteins compared to blade-based homogenizers. Process Biochem 5 (5) 859–866DOI


Buyel JF, Fischer R (2015) Synthetic polymers are more effective than natural flocculants for the clarification of tobacco leaf extracts. J Biotechnol 195, 37–42.  DOI


Buyel JF, Gruchow HM, Fischer R (2015) Depth filters containing diatomite achieve more efficient particle retention than filters solely containing cellulose fibers. Front Plant Sci 6, 1134.  DOI


Buyel JF, Opdensteinen P, Fischer R (2015) Cellulose-based filter aids increase the capacity of depth filters during the downstream processing of plant-derived biopharmaceutical proteins. Biotechnol J 10 (4) 584–591.  DOI


Chang S, Berman J, Sheng Y, Wang Y, Capell T, Shi L, Ni X, Sandmann G, Christou P, Zhu C (2015) Cloning and functional characterization of the maize (Zea mays L.) carotenoid epsilon hydroxylase gene. PLOS One 10 (6) e0128758.  DOI


Chocarro C, Lloveras J (2015) The effect of row spacing on alfalfa seed and forage production under irrigated Mediterranean agricultural conditions. Grass Forage Sci 70 (4) 651–660.  DOI


Cremer C, Braun H, Mladenov R, Hein L, Cong X, Jost E, Brümmendorf TH, Fischer R, Carloni P, Barth S, Nachreiner T (2015) Novel angiogenin mutants with increased cytotoxicity enhance the depletion of pro-inflammatory macrophages and leukemia cells ex vivo. Cancer Immunol Immunother 64 (12) 1575–1586.  DOI


Cremer C, Vierbuchen T, Hein L, Fischer R, Barth S, Nachreiner T (2015) Angiogenin mutants as novel effector molecules for the generation of fusion proteins with increased cytotoxic potential. J Immunother 38 (3) 85–95.  DOI


Dickmeis C, Honickel MM, Fischer R, Commandeur U (2015) Production of hybrid chimeric PVX particles using a combination of TMV and PVX-based expression vectors. Front Bioeng Biotechnol 3, 189.  DOI


Epping J, van Deenen N, Niephaus E, Stolze A, Fricke J, Huber C, Eisenreich W, Twyman RM, Prüfer D, Schulze Gronover C (2015) A rubber transferase activator is necessary for natural rubber biosynthesis in dandelion. Nature Plants 1, 15048.  DOI


Ferrarini A, Xumerle L, Griggio F, Garonzi M, Cantaloni C, Centomo C, Vargas SM, Descombes P, Marquis J, Collino S, Franceschi C, Garagnani P, Salisbury BA, Harvey JM, Delledonne M (2015) The use of non-variant sites to improve the clinical assessment of whole-genome sequence data. PLOS One 10 (7) e0132180.  DOI


Filippetti I, Movahed N, Allegro G, Valentini G, Pastore C, Colucci E, Intrieri C (2015) Effect of post-veraison source limitation on the accumulation of sugar, anthocyanins and seed tannins in Vitis vinifera cv. Sangiovese berries. Aust J Grape Wine Res 21 (1) 90–100.  DOI


Fitting J, Blume T, Ten Haaf A, Blau W, Gattenlöhner S, Tur MK, Barth S (2015) Generation of novel internalizing antibody fragments by phage display for immunotoxin-based treatment of acute myeloid leukemia. Monoclon Antib 7 (2) 390–402.  DOI


Fritsch L, Fischer R, Schillberg S, Wamback C, Schröper F (2015) Next-generation sequencing is a robust strategy for the detection of zygosity in transgenic maize. Transgenic Res 24 (4) 615–623.  DOI


Kaiser M, Pereira S, Pohl L, Ketelhut, Kemper B, Gorzelanny, Galla HJ, Moerschbacher BM, Goycoolea FM (2015) Chitosan encapsulation modulates the effect of capsaicin on the tight junctions of MDCK cells. Sci Rep 5, 10048.  DOI


Kapelski S, Boes A, Spiegel H, de Almeida M, Klockenbring T, Reimann A, Fischer R,  Barth S, Fendel R (2015) Fast track antibody V-gene rescue, recombinant expression in plants and characterization of a PfMSP4-specific antibody. Malaria J 14, 50.  DOI


Kapelski S, de Almeida M, Fischer R, Barth S, Fendel R (2015) Antimalarial activity of granzyme B and its targeted delivery by a granzyme B–single-chain Fv fusion protein. Antimicrob Agents Chemother 59 (1) 669–672.  DOI


Klinger J, Fischer R, Commandeur U (2015) Comparison of Thermobifida fusca cellulases expressed in Escherichia coli and Nicotiana tabacum indicates advantages of the plant system for the expression of bacterial cellulases. Front Plant Sci 6, 1047.  DOI


Knorr E, Schmidtberg H, Arslan D, Bingsohn L, Vilcinskas A (2015) Translocation of bacteria from the gut to the eggs triggers maternal transgenerational immune priming in Tribolium castaneum. Biol Lett 11 (12) 20150885.  DOI


Hamer SN, Cord-Landwehr S, Biarnés X, Planas A, Waegeman H, Moerschbacher BM, Kolkenbrock S (2015) Enzymatic production of defined chitosan oligomers with a specific pattern of acetylation using a combination of chitin oligosaccharide deacetylases. Sci Rep 5, 8716.  DOI


Hristodorov D, Mladenov R, von Felbert V, Huhn M, Fischer R, Barth S, Thepen T (2015) Targeting CD64 mediates elimination of M1 but not M2 macrophages in vitro and in cutaneous inflammation in mice and patient biopsies. Monoclon Antib 6 (5) 853–862.  DOI


Laibach N, Hillebrand A, Twyman RM, Prüfer D, Schulze Gronover C (2015) Identification of a rubber elongation factor protein in Taraxacum brevicorniculatum that is localized on rubber particles and promotes rubber biosynthesis. Plant J 82 (4) 609–620.  DOI


Lampis S, Santi C, Ciurli A, Andreolli M, Vallini G (2015) Promotion of arsenic phytoextraction efficiency in the fern Pteris vittata by the inoculation of As-resistant bacteria: a soil bioremediation perspective. Front Plant Sci 6, 80.  DOI


Leufken CM, Moerschbacher BM, Dirks-Hofmeister ME (2015) Dandelion PPO-1/PPO-2 domain-swaps: The C-terminal domain modulates the pH optimum and the linker affects SDS-mediated activation and stability. Biochim Biophys Acta 1854 (2) 178–186.  DOI


Ma JKC, Drossard J, Lewis D, Altmann F, Boyle J, Christou P, Cole T, Dale P, van Dolleweerd CJ, Isitt V, Katinger D, Lobedan M, Mertens H, Paul MJ, Rademacher T, Sack M, Hundleby PAC, Stiegler G, Stoger E, Twyman RM, Vcelar B, Fischer R (2015) Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants. Plant Biotechnol J 13 (8) 1106–1120.  DOI


Madhuprakash J, El Gueddari NE, Moerschbacher BM, Podile AR (2015) Catalytic efficiency of chitinase-D on insoluble chitinous substrates was improved by fusing auxiliary domains. PLOS One 10 (1) e0116823.  DOI


Madhuprakash J, El Gueddari NE, Moerschbacher BM, Podile AR (2015) Production of bioactive chitosan oligosaccharides using the hypertransglycosylating chitinase-D from Serratia proteamaculans. Bioresource Technol 198, 503–509.  DOI


Maskus DJ, Bethke S, Seidel M, Kapelski S, Addai-Mensah O, Boes A, Edgü G, Spiegel H, Reimann A, Fischer R, Barth S, Klockenbring T, Fendel R (2015) Isolation, production and characterization of fully human monoclonal antibodies directed to Plasmodium falciparum MSP10. Malar J 14, 276.  DOI


Menchicchi B, Fuenzalida JP, Hensel A, Swamy MJ, David L, Rochas C, Goycoolea FM (2015) Biophysical analysis of the molecular interactions between polysaccharides and mucin. Biomacromolecules 16 (3) 924–935.  DOI


Mendonça D, Luna S, Bettencourt S, Lopes MS, Monteiro L, Neves JD, Monjardino P, da Câmara Machado A (2015) In vitro propagation of Picconia azorica (Tutin) Knobl. (Oleaceae) an Azorean endangered endemic plant species. Acta Physiol Plant 37, 47.  DOI


Milia G, Camiolo S, Avesani L, Porceddu A (2015) The dynamic loss and gain of introns during the evolution of the Brassicaceae. Plant J 82 (6) 915–924.  DOI


Mladenov R, Hristodorov D, Thepen T, Cremer C, Hein L, Niesen J, Brehm H, Brümmendorf T, Jost E, Fischer R, Stockmeyer B, Barth S, Stein C (2015) The Fc-alpha receptor is a new immunotherapeutic target antigen for the treatment of myeloid leukaemia. Int J Cancer 137 (11) 27292738.  DOI


Niesen J, Brehm H, Stein C, Berges N, Pardo A, Fischer R, Ten Haaf A, Gattenlöhner S, Tur MK, Barth S (2015) In vitro effects and ex vivo binding of an EGFR-specific immunotoxin on rhabdomyosarcoma cells. J Cancer Res Clin Oncol 141 (6) 1049–1061.  DOI


Niesen J, Stein C, Brehm H, Hehmann-Titt G, Fendel R, Melmer G, Fischer R,  Barth S (2015) Novel EGFR-specific immunotoxins based on panitumumab and cetuximab show in vitro and ex vivo activitu against different tumor entities. J Cancer Res Clin Oncol 141 (12) 2079–2095.  DOI

O'Keeffe C, Champion S, Allsop D (2015) Demonstrating the effect of forensic firearm countermeasures: Bullet characteristics generated due to barrel modifications. Forensic Sci Int 257, 13–19.  DOI

Popovic M, Prodanovic R, Ostafe R, Schillberg S, Fischer R, Gavrovic-Jankulovic M (2015) Yeast surface display is a novel tool for the rapid immunological characterization of plant plant-derived food allergens. Immunologic Res 61 (3) 230–239.  DOI


Pöppel AK, Vogel H, Wiesner J, Vilcinskas A (2015) Combinatorial activities of antimicrobial peptides expressed in medicinal maggots of the blow fly Lucilia sericata against bacteria.  Antimicrob Agents Chemother 59 (9) 2508–2514.  DOI


Rahnamaeian M, Cytrynska M, Zdybicka-Barabas A, Dobslaff K, Twyman RM, Züchner T, Sadd B, Regoes R, Schmid-Hempel P, Vilcinskas A (2015) Insect antimicrobial peptides show potentiating functional interactions against Gram-negative bacteria. Proc R Soc B 282 (1806) 20150293.  DOI


Raven N, Rasche S, Kuehn C, Anderlei T, Klöckner W, Schuster F, Fischer R, Henquet M, Bosch D, Büchs J, Schillberg S (2015) Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200 L orbitally shaken disposable bioreactor. Biotechnol Bioeng 112 (2) 308–321.  DOI


Rettcher S, Jungk F, Kühn C, Krause HJ, Nölke G, Commandeur U, Fischer R, Schillberg S, Schröper F (2015) A simple and portable magnetic immunoassay for the rapid detection and sensitive quantitation of plant viruses. Appl Microbiol Biotechnol 81 (18) 3039–3048.   DOI


Sack M, Rademacher T, Spiegel H, Boes A, Hellwig S, Drossard J, Stoger E, Fischer R (2015) From gene to harvest: Insights into upstream process development for the GMP production of a monoclonal antibody in transgenic tobacco plants. Plant Biotechnol J 13 (8) 1094–1105.  DOI


Santos-Carballal B, Aaldering LJ, Ritzefeld M, Pereira S, Sewald N, Moerschbacher BM, Götte M, Goycoolea FM (2015) Physicochemical and biological characterization of chitosan-microRNA nanocomplexes for gene delivery to MCF-7 breast cancer cells. Sci Rep 5, 13567.  DOI


Schlich K, Hund-Rinke K (2015) Influence of soil properties on the effect of silver nanomaterials on microbial activity in five soils. Environ Poll 196 (1) 321–330.  DOI


Schott M, Klein B, Vilcinskas A (2015) Sniffer bees: Detection of illicit drugs by trained honeybees (Apis mellifera). PLOS One 10 (6) e0128528.  DOI

Schubert M, Houdelet M, Kogel KH, Fischer R, Schillberg S, Nölke G (2015) Thanatin confers partial resistance against aflatoxigenic fungi in maize (Zea mays). Transgenic Res 24 (5) 885–895.  DOI

Shukla S, DiFranco NA, Wen AM, Commandeur U, Steinmetz NF (2015) To target or not to target: active vs. passive tumor homing of filamentous nanoparticles based on Potato virus X. Cel Mol Bioeng 8 (3) 433–444.  DOI


Shukla S, Eber FJ, Nagarajan AS, DiFranco NA, Schmidt N, Wen AM, Eiben S, Twyman RM, Wege C, Steinmetz NF (2015) The impact of aspect ratio on the biodistribution and tumor homing of rigid soft-matter nanorods. Adv Healthc Mater 4 (6) 874–882.  DOI


Sonnack L, Kampe S, Muth-Köhne E, Erdinger L, Henny N, Hollert H, Schäfers C, Fenske M (2015) Effects of metal exposure on motor neuron development, neuromasts and the escape response of zebrafish embryos. Neurotoxicol Teratol 50, 33–42.  DOI


Spohner SC, Zahn D, Schaum V, Quitmann H, Czermak P (2015)  Recombinant alpha-L-rhamnosidase from Aspergillus terreus in selective trimming of alpha-L-rhamnose from steviol glycosides. J Mol Cat B: Enzymatic 122 (12) 248–254.  DOI


Spiegel H, Boes A, Kastilan R, Kapelski S, Edgue G, Beiss V, Chubodova I, Schillberg S, Reimann A, Fischer R (2015) The stage-specific in vitro efficacy of a malaria antigen cocktail provides valuable insights into the development of effective multi-stage vaccines. Biotechnol J 10 (10) 1651–1659.  DOI


Spiegel H, Boes A, Voepel N, Beiss V, Edgue G, Rademacher T, Sack M, Schillberg S, Reimann A, Fischer R (2015) Application of a scalable plant transient gene expression platform for malaria vaccine development. Front Plant Sci 6, 1169.  DOI


Spiegel H, Schinkel H, Kastilan R, Dahm P, Boes A, Scheuermayer M, Chudobová I, Maskus D, Fendel R, Schillberg S, Reimann A, Fischer R (2015) Optimization of a multi-stage, multi-subunit malaria vaccine candidate for the production in Pichia pastoris by the identification and removal of protease cleavage sites. Biotechnol Bioeng 112 (4) 659–667.  DOI


Stöveken J, Singh R, Kolkenbrock S, Zakrzewski M, Wibberg D, Eikmeyer FG, Pühler A, Schlüter A, Moerschbacher BM (2015) Successful heterologous expression of a novel chitinase identified by sequence analyses of the metagenome from a chitin-enriched soil sample. J Biotechnol 201, 60–68.  DOI


Ten Haaf A, Pscherer S, Fries K, Barth S, Gattenlöhner S, Tur MK (2015) Phage display-based on-slide selection of tumor-specific antibodies on formalin-fixed paraffin-embedded human tissue biopsies. Immunol Lett 166 (2) 65–78.  DOI


Tinazzi E, Merlin M, Bason C, Beri R, Zampieri R, Lico C, Bartoloni E, Puccetti A, Lunardi C, Pezzotti M, Avesani L (2015) Plant-derived chimeric virus particles for the diagnosis of primary Sjögren syndrome. Front Plant Sci 6, 1080.  DOI


Tonk M, Cabezas-Cruz A, Valdés JJ, Rego RO, Grubhoffer L, Estrada-Peña A, Vilcinskas A, Kotsyfakis M, Rahnamaeian M (2015) Ixodes ricinus defensins attack distantly-related pathogens. Dev Comp Immunol 53 (2) 358–365.  DOI


Tonk M, Knorr E, Cabezas-Cruz A, Valdés JJ, Kollewe C, Vilcinskas A (2015) Tribolium castaneum defensins are primarily active against Gram-positive bacteria. J Invertebrate Pathol 132, 208–215.  DOI


van Rijn P, van Bezouwen LS, Fischer R, Boekema EJ, Böker A, Commandeur U (2015) Virus-SiO2 and virus-SiO2-Au hybrid particles with tunable morphology. Part Part Syst Charact 32 (1) 43–47.  DOI


Will T, Vilcinskas A (2015) The structural sheath protein of aphids is required for phloem feeding. Insect Biochem Mol Biol 57, 3440.  DOI


Zenaro E, Pietronigro E, Bianca VD, Piacentino G, Marongiu L, Budui S, Turano E, Rossi B, Angiari S, Dusi S, Montresor A, Carlucci T, Nanì S, Tosadori G, Calciano L, Catalucci D, Berton G, Bonetti B, Constantin G (2015) Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin. Nature Med 21 (8) 880886.  DOI



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