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Description
Description
Description
Twyman
Research
Management Ltd
Description
Specialist consultants in scientific project development, management and presentation

Richard Twyman's Published Articles (2015-2018)

 2018 

Beinecke FA, Grundmann L, Wiedmann DR, Schmidt FJ, Caesar AS, Zimmermann M, Lahme M, Twyman RM, Prüfer D, Noll GA (2018) The FT/FD-dependent initiation of flowering under long-day conditions in the day-neutral species Nicotiana tabacum originates from the facultative short-day ancestor N. tomentosiformis
The Plant Journal 96 (2) 329342.  DOI

Fischer R, Holland T, Sack M, Schillberg S, Stoger E, Twyman RM, Buyel JF (2018) Glyco-engineering of plant-based expression systems. 
Advances in Biochemical Engineering/Biotechnology (online first).  DOI

Unland K, Pütter K, Vorwerk K, van Deenen N, Twyman RM, Prüfer D, Schulze Gronover C (2018) Functional characterization of squalene synthase and squalene epoxidase in Taraxacum koksaghyz
Plant Direct 2 (6) e00063.  DOI

Vamvaka E, Farré G, Molinos-Albert LM, Evans A, Canela-Xandri A, Twyman RM, Carrillo J, Ordóñez RA, Shattock RJ, O’Keefe BR, Clotet B, Blanco J, Khush GS, Christou P, Capell T (2018) Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm.
Proceedings of the National Academy of Sciences USA 115 (33) E7854E7862.  DOI

Zhu C, Farré G, Zanga D, Lloveras J, Michelena A, Ferrio JP, Voltas J, Slafer G, Savin R, Albajes R, Eizaguirre M, Lopez C, Cantero-Martínez C, Díaz-Gómez J, Nogareda C, Moreno JA, Angulo E, Estany J, Pena RN, Tor M, Portero-Otin M, Eritja N, Arjó G, Serrano JCE, Matias-Guiu X, 
Twyman RM, Sandmann G, Capell T, Christou P (2018) High-carotenoid maize: development of plant biotechnology prototypes for human and animal health and nutrition. 
Phytochemistry Reviews 17 (2) 195209.  DOI


 2017 

Buyel JF, Twyman RM, Fischer R (2017) Very-large-scale production of antibodies in plants: the biologization of manufacturing. 
Biotechnology Advances 35 (4) 458465.  DOI 

Díaz-Gómez J, Twyman RM, Zhu C, Farré G, Serrano JCE, Portero-Otin M, Muñoz P, Sandmann G, Capell T, Christou P (2017) Biofortification of crops with nutrients: factors affecting utilization and storage. 
Current Opinion in Biotechnolog44, 115123.  DOI 

Edgue G, Twyman RM, Beiss V, Fischer R, Sack M (2017) Antibodies from plants for bionanomaterials. 
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 9 (6) e1462.  DOI

Zhu C, Bortesi L, Baysal C, Twyman RM, Fischer R, Capell T, Schillberg S, Christou P (2017) Characteristics of genome editing mutations in cereal crops. 
Trends in Plant Science 22 (1) 3852.  DOI 


 2016 

Boes A, Reimann A, Twyman RM, Fischer R, Schillberg S, Spiegel H (2016) A plant-based transient expression system for the rapid production of malaria vaccine candidates. 
Methods in Molecular Biology 1404, 597–619.  DOI  

Bortesi L, Zhu C, Zischewski J, Perez L, Bassié L, Nadi R, Forni G, Lade S, Soto E, Jin X, Medina V, Villorbina G, Munoz P, Farré G, Fischer R, Twyman RM, Capell T, Christou P, Schillberg S (2016) Patterns of CRISPR/Cas9 activity in plants, animals and microbes.
Plant Biotechnology Journal 14 (12) 2203–2216.  DOI 

Lee KL, Twyman RM, Fiering S, Steinmetz NF (2016) 
Virus-based nanoparticles as platform technologies for modern vaccines. 
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 8 (4) 544–578.  DOI  


Moreno JA, Díaz-Gómez J, Nogareda C, Angulo E, Sandmann G, Portero-Otin M, Serrano JCE, Twyman RM, Capell T, Zhu C, Christou P (2016) The distribution of carotenoids in hens fed on biofortified maize is influenced by feed composition, absorption, resource allocation and storage. 

Scientific Reports 6, 35346.  DOI 


Vamvaka E, Twyman RM, Murad AM, Melnik S, Teh AYH, Arcalis E, Altmann F, Stoger E, Rech E, Ma JKC, Christou P, Capell T (2016) Rice endosperm produces an underglycosylated and potent form of the HIV-neutralizing monoclonal antibody 2G12. 

Plant Biotechnology Journal 14 (1) 97–108.  DOI  



 2015 

Berman J, Zorrilla-López U, Farré G, Zhu C, Sandmann G, Twyman RM, Capell T, Christou P (2015) Nutritionally important carotenoids as consumer products. 
Phytochemistry Reviews 14 (5) 727–743.  DOI  

Buyel JF, Fischer R, Twyman RM (2015) Extraction and downstream processing of plant-derived recombinant proteins.  
Biotechnology Advances 33 (6.1) 902–913.  DOI  

Epping J, van Deenen N, Niephaus E, Stolze A, Fricke J, Huber C, Eisenreich W, Twyman RM, Prüfer D, Schulze Gronover C (2015) A rubber transferase activator is necessary for natural rubber biosynthesis in dandelion. 

Nature Plants 1, 15048.  DOI  


Farré G, Twyman RM, Christou P, Capell T, Zhu C (2015) Knowledge-driven approaches for engineering complex metabolic pathways in plants. 

Current Opinion in Biotechnology 32, 54–60.  DOI  


Fischer R, Vasilev N, Twyman RM, Schillberg S (2015) High-value products from plants: the challenges of process optimization. 

Current Opinion in Biotechnology 32, 156–162.  DOI   


Laibach N, Hillebrand A, Twyman RM, Prüfer D, Schulze Gronover C (2015) Identification of a rubber elongation factor protein in Taraxacum brevicorniculatum which is localized on rubber particles and promotes rubber biosynthesis. 

The Plant Journal 82 (4) 609–620.  DOI  


Laibach N, Post J, Twyman RM, Schulze Gronover C, Prüfer D (2015) The characteristics and potential applications of structural lipid droplet proteins in plants. 

Journal of Biotechnology 201, 15–27.  DOI  


Ma JKC, Drossard J, Lewis D, Altmann F, Boyle J, Christou P, Cole T, Dale P, van Dolleweerd CJ, Isitt V, Katinger D, Lobedan M, Mertens H, Paul MJ, Rademacher T, Sack M, Hundleby PAC, Stiegler G, Stoger E, Twyman RM, Vcelar B, Fischer R (2015) Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants. 

Plant Biotechnology Journal 13 (8) 1106–1120.  DOI  


Mukherjee K, Twyman RM, Vilcinskas A (2015) Insects as models to study the epigenetic basis of disease. 

Progress in Biophysics and Molecular Biology 118 (1–2) 69–78.  DOI  


Rahnamaeian M, Cytrynska M, Zdybicka-Barabas A, Dobslaff K, Twyman RM, Züchner T, Sadd B, Regoes R, Schmid-Hempel P, Vilcinskas A (2015) Insect antimicrobial peptides show potentiating functional interactions against Gram-negative bacteria. 

Proceedings of the Royal Society B: Biological Sciences 282 (1806) 20150293.  DOI  


Shukla S, Eber FJ, Nagarajan AS, DiFranco NA, Schmidt N, Wen AM, Eiben S, Twyman RM, Wege C, Steinmetz NF (2015) The impact of aspect ratio on the biodistribution and tumor homing of rigid soft-matter nanorods. 

Advanced Healthcare Materials 4 (6) 874–882.  DOI  


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