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Richard Twyman's Website Articles

As well as developing various project websites as listed here, Richard Twyman has worked extensively on website text including a large number of articles for the Wellcome Trust Human Genome Project Microsite and the gene and protein lists for the Wellcome Trust Chromosome Browser.  

 

2007 Wellcome Science articles

 

Biobanks: the long game

 

Small RNA: big news

 

 

2004/2005  'Genes and disease' series

 

Huntington's disease

 

Duchenne and Becker muscular dystrophy

 

Haemophilia A and B

 

Fragile-X syndrome

 

Achondroplasia

 

Down's syndrome

 

Hereditary haemochromatosis

 

Cystic fibrosis

 

 

2003 'Tackling disease' series

 

RNA interference: silencing is golden

 

Tissue matching for transplants

 

Viagra

 

Captopril

 

Angiozyme

 

Gleevec

 

Herceptin

 

Rational drug design

 

DNA vaccines

 

DNA arrays and cancer classification

 

Proteomics and cancer diagnosis

 

 A brief history of clinical trials

 

Clinical trials

 

Gene therapy

 

Xenotransplantation

 

Drug development

 

Genetic modification of pigs for xenotransplantation

  

 

2003 'Genes and disease' background articles

 

Recessive diseases

 

Single-gene disorders

 

Dominant diseases

 

X-linked diseases

 

Polygenic and multifactorial disorders

 

Chromosome abnormalities

 

Imprinting disorders

 

Genes and infectious disease

 

 

2003 'Human variation' background articles

 

Pharmacogenomics

 

Genes and drug responses

 

Linkage analysis

 

Haplotype mapping

 

Single nucleotide polymorphisms

 

Mutations and polymorphisms

 

Simple sequence repeats

 

Haplotype mapping ethics

 

The International HAPMAP project

 

 

2003 'Technology centre' series

 

Transgenic mice

 

Metabolomics

 

Mass spectrometry

 

Gene expression

 

Protein interaction mapping

 

Gene structure

 

Epigenetics

 

Protein structure

 

Proteomics

 

Transcriptomics

 

DNA microarrays

 

X-ray crystallography

 

Nuclear magnetic resonance imaging

 

DNA sequencing

 

Animal cloning

 

Gene knockout in mice

 

Polymerase chain reaction

 

Combinatorial library screening

 

SNP typing with DNA chips

 

Proteomics and toxicology

 

  

2002-2003 'In the genome' series

 

The mitochondrial genome

 

Comparative genomics

 

The major histocompatibility complex

 

Centromeres

 

Telomeres

 

 

2002 'How the body works' series

 

Model organisms: overview

 

Model organisms: yeast

 

Model organisms: fish

 

Model organisms: frogs and chickens

 

Model organisms: mice

 

Model organisms: fruit flies

 

Model organisms: worms

 

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